Learning Medical Risk Scores for Pediatric Appendicitis

Pedro Roig Aparicio, Ricards Marcinkevics, Patricia Reis Wolfertstetter, S. Wellmann, C. Knorr, Julia E. Vogt
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引用次数: 7

Abstract

Appendicitis is a common childhood disease, the management of which still lacks consolidated international criteria. In clinical practice, heuristic scoring systems are often used to assess the urgency of patients with suspected appendicitis. Previous work on machine learning for appendicitis has focused on conventional classification models, such as logistic regression and tree-based ensembles. In this study, we investigate the use of risk supersparse linear integer models (risk SLIM) for learning data-driven risk scores to predict the diagnosis, management, and complications in pediatric patients with suspected appendicitis on a dataset consisting of 430 children from a tertiary care hospital. We demonstrate the efficacy of our approach and compare the performance of learnt risk scores to previous analyses with random forests. Risk SLIM is able to detect medically meaningful features and outperforms the traditional appendicitis scores, while at the same time is better suited for the clinical setting than tree-based ensembles.
学习儿科阑尾炎的医疗风险评分
阑尾炎是一种常见的儿童疾病,其管理仍缺乏统一的国际标准。在临床实践中,启发式评分系统常用于评估疑似阑尾炎患者的急迫性。以前关于阑尾炎机器学习的工作主要集中在传统的分类模型上,如逻辑回归和基于树的集成。在这项研究中,我们研究了使用风险超稀疏线性整数模型(risk SLIM)来学习数据驱动的风险评分,以预测疑似阑尾炎的儿科患者的诊断、管理和并发症,数据集包括来自三级医疗医院的430名儿童。我们证明了我们的方法的有效性,并将学习风险评分的性能与之前的随机森林分析进行了比较。Risk SLIM能够检测到医学上有意义的特征,并且优于传统的阑尾炎评分,同时比基于树的集合更适合临床环境。
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