Manifestations articulaires de la maladie de Lyme

Christelle Sordet
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Abstract

Lyme Borreliosis is a polyvisceral infectious disease due to Borrelia burgdorferi sensu lato transmitted by tick bite. Although the disease can evolve through different stages with mainly dermatological and neurological attacks, the typical clinical picture is that of monoarthritis of the knee. It is not always preceded by earlier stages such as erythema migrans. Its diagnosis is based on a combination of amnestic, clinical and biological criteria. Elisa and Western blot serology are always positive for Ig G. Treatment is based on antibiotic therapy for 28 days with doxycycline 200 mg/d. The evolution is generally favourable with in the majority of cases a restitution ad integrum. Polyalgesic syndromes with positive Lyme serology and a history of confirmed or suspected Lyme borreliosis must be treated with particular care, and diagnostic approach must be rigorous in order not to overlook differentials diagnosis which are many. Repeated antibiotic treatment does not improve these clinical pictures.

莱姆病的关节表现
莱姆病是一种由蜱叮咬传播的伯氏疏螺旋体引起的多内脏传染病。虽然疾病可以发展到不同的阶段,主要是皮肤和神经的攻击,典型的临床表现是单膝关节炎。它并不总是发生在早期阶段,如红斑移动性。它的诊断是基于遗忘,临床和生物学标准的结合。Elisa和Western blot血清学Ig g均呈阳性,治疗基础为抗生素治疗28天,多西环素200mg /d。这种演变通常是有利的,在大多数情况下是恢复和整合。具有莱姆病血清学阳性和确诊或疑似莱姆病borreliosis病史的多痛综合征必须特别小心治疗,诊断方法必须严格,以免忽视许多鉴别诊断。反复的抗生素治疗并不能改善这些临床症状。
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