Factors responsible for developing common oral antibiotic resistant to urinary tract infection (UTI) among the children

Abstract

The present study is designed to access the factors responsible for developing recurring infection and antibiotic resistance among children with urinary tract infection (UTI). The socio-demographic characteristics of the respondents are important to determine the level of awareness regarding antibiotic resistance; 16.1% children were between 1 to 5 years of age, 21.9% between 5.1 to 9 years, 29.9% between 9.1 to 12 years and 32.1% between 12.1 to 15 years of age who were suffering from UTI. Out of 137 children, 17.5% males were suffering from UTI and the rest 82.5% were females; it reveals that 34.3% children intakes less than 500 ml of water every day while 40.1% intakes 500 to 1000 ml of water, 21.1% children take about 1000 to 1500 ml of water and only 4.4% intakes more than 1500 ml of water every day. The present investigation showed that 50.4% of the children had a history of taking antibiotics while 29.9% did not know whether the child had a history of taking antibiotics and 5.8% has no history of taking antibiotic. Out of the 81 children who received treatment for UTI, 76.5% were fully cured after receiving antibiotic while 19.8% were not cured after taking antibiotic. Out of the 43 children who took the antibiotic on time, 79% took it for 1 to 3 days, 16.3% took it for 3 to 5 days and 4.7% took it for 5 to 7 days. Positive correlation found with male children, maintaining toilet hygiene and recurrent UTI.54.4% respondent used water to maintain the child’s toilet hygiene suffered from recurrent UTI and 92.8% respondent used other means excluding water to maintain the child’s toilet hygiene suffered from recurrent UTI (p<0.05). The major factors for developing recurrent UTI and resistance to certain antibiotics are taking medicine from pharmacy, doing self-prescription, incomplete medication courses along with lack of hygiene and insufficient water intake. There should be rational use of antibiotic and culture sensitivity for urine should be a mandatory test before administering antibiotics for UTI. There is need to build awareness about antibiotic resistance through health campaigns.