A Case of Canine Lymphocytosis with a Prominent Skin Lesion

T. Fukutomi, N. Yamamoto, H. Kondo, H. Shibuya, T. Watari, R. Kano, H. Kamata
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Abstract

: A 9-year-old female mixed-breed dog presented with alopecia, squama, scaling, erosion, and hyperpigmentation that had persisted for three months. Histopathological assessment of a skin biopsy, bone marrow aspiration, and fine needle aspiration of the liver and spleen revealed lymphocyte hyperplasia. A blood cell count also indicated severe lymphocytosis. These findings were consistent with lymphocytosis accompanied by cutaneous lesions, and not neoplastic proliferation of lymphocytes or any other pathology. The dog was treated with antibiotic, antimycotic, dietary therapy, and interferon therapy, and achieved remission of skin lesion and lymphocytosis on steroid therapy.
犬淋巴细胞增多症伴明显皮肤病变1例
:一只9岁的雌性混血狗,表现为脱发、鳞片、脱屑、糜烂和色素沉着,持续了3个月。皮肤活检、骨髓穿刺和肝脾细针穿刺的组织病理学评估显示淋巴细胞增生。血细胞计数也显示严重的淋巴细胞增多。这些发现与伴有皮肤病变的淋巴细胞增多一致,而不是淋巴细胞的肿瘤增生或任何其他病理。狗接受抗生素、抗真菌药、饮食治疗和干扰素治疗,类固醇治疗后皮肤病变和淋巴细胞增多症得到缓解。
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