Biocide activity against Legionella and Pseudomonas

Sue Page, Christine Gaylarde
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引用次数: 14

Abstract

Four biocides were tested for their abilities to kill Legionella micdadei and Pseudomona fluorescens in a buffered saline solution. The most effective against both organisms, at concentrations of 50 ppm or above, was a phosphonium compound, but this biocide failed to produce a 99·9% kill of P. fluorescens within 24 h at concentrations below 50 ppm. All chemicals apart from an oxidisingbiocide were more effective against L. micdadei than P. fluorescens. Old cells of Legionella, but not of Pseudomonas, exhibited increased resistance against BNPD. This could be associated with an altered outer envelope, demonstrated by SDS-PAGE analysis.

军团菌和假单胞菌的杀菌剂活性
在缓冲盐水溶液中测试了四种杀菌剂杀灭米氏军团菌和荧光假单胞菌的能力。在浓度为50ppm或以上时,对这两种生物最有效的杀菌剂是磷化合物,但在浓度低于50ppm时,该杀菌剂在24小时内无法产生99.9%的荧光假单胞菌杀灭率。除氧化杀菌剂外,所有化学药剂对米氏乳杆菌的杀灭效果均优于荧光假单胞菌。军团菌的老细胞,而假单胞菌的老细胞,对BNPD的抵抗力增强。SDS-PAGE分析表明,这可能与外包膜的改变有关。
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