Development of Antimalarial Pharmacotherapy and its importance in Malaria Treatment/Public Health Program

Anil K Agarwal, A. Yadav, C. P, Paromita Kuity, Jaya Mishra
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Abstract

Aim/Objective: The primary objective of this review is to describe the Evolution of current allopathic Anti-malarial Pharmacotherapy and understanding significance of Antimalarial drugs in Malaria Program/Public Health Program in India. Subject/Method: Review of Research Literature and Context-Content-Outcome Analysis of Antimalarial Drug Policy. Findings: Antimalarial drug list expanded extensively and the drug dose intensity is proportional to disease transmission in region/area; both the factors medicalizing the community significantly. The conceptual understanding of malaria remains within biomedicine domain evidenced by the fact that much of importance (over-reliance) given to least effective individual level technical interventions like drugs that too; without considering immunity and nutritional status of both individual and community. Indian Planners seems confused to differentiate (or ignoring) between Malaria’s behavior at Individual level and community level. Thus, the Malaria planning lacks ethical consideration for resource allocation in Public Health Planning evidenced by the fact that large resources allocated to least effective intervention that serves the profit making purpose of private sector pharma industry. Sufferings of the most impoverished household of community remain unaddressed in Health planning. Policy for Antimalarial Pharmacotherapy is unable to serve its primary purpose of relieving suffering of community, prevention of mortalities, reducing morbidities, slowing down the resistance, and reducing drug load in community. Conclusion: The investment in medications to tackle malaria as Public Health problem looks costly investments as it consumes heavy resources and its benefits/success claim is questionable. There is mismatch in planning and field reality as intervention in the form of drugs does not match the requirement as per epidemiological complexity. Health Planning is comprehensive exercise for any country. Ignoring voices from field/frontline workers prove detrimental for health planning. Every organization or individual involved in health planning would be having different opinions as per their interest but the final decision regarding resource allocation should consider the field reality following good public health ethics.
抗疟药物治疗的发展及其在疟疾治疗/公共卫生规划中的重要性
目的/目的:本综述的主要目的是描述当前对抗疗法抗疟疾药物治疗的发展,并了解抗疟疾药物在印度疟疾计划/公共卫生计划中的意义。主题/方法:研究文献综述及抗疟药物政策的背景-内容-结果分析。结果:抗疟药物目录广泛扩展,药物剂量强度与地区/地区疾病传播成正比;这两个因素都使社区医疗化。对疟疾的概念性理解仍然局限于生物医学领域,事实证明,对最不有效的个人层面技术干预措施(如药物)的重视(过度依赖)也很重要;不考虑个人和社区的免疫和营养状况。印度的规划者似乎对区分(或忽视)疟疾在个人层面和社区层面的行为感到困惑。因此,疟疾规划在公共卫生规划中缺乏对资源分配的伦理考虑,事实证明,大量资源分配给了服务于私营部门制药行业盈利目的的最不有效的干预措施。社区最贫困家庭的苦难在卫生规划中仍未得到解决。抗疟药物治疗政策无法达到减轻社区痛苦、预防死亡、降低发病率、减缓耐药性和减少社区药物负荷的主要目的。结论:将疟疾作为公共卫生问题的药物的投资看起来是昂贵的投资,因为它消耗大量资源,其效益/成功的说法值得怀疑。由于以药物形式进行的干预不符合流行病学复杂性的要求,规划与现场实际情况不匹配。健康规划对任何国家来说都是一项全面的锻炼。忽视现场/一线工作人员的声音不利于卫生规划。参与卫生规划的每个组织或个人都会根据自己的利益有不同的意见,但有关资源分配的最终决定应遵循良好的公共卫生道德,考虑实地的现实情况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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