Association between Herpes Simplex Type 1 Virus Infection and Bell’s Palsy

Bangladesh Journal of Neuroscience Pub Date : 2016-01-31 DOI:10.3329/bjn.v32i1.57407

M. Islam, S. Sarkar, P. Das, T. Rahman, S. F. Sazib

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Abstract

Background: Idiopathic facial paralysis is one of the commonest conditions in neurological practice. Objective: The purpose of this study is to see whether Bell’s palsy is associated with serological marker of Herpes Simplex virus type 1, and to study the clinical signs and symptoms manifested by Bell’s palsy. Methodology: This retrospective observational study was carried out in neurology OPD of ShSMCH, Dhaka from June, 2014 to May, 2016. All the patients who came to the OPD were selected as study population. All relevant data, those who fulfill the inclusion criteria were recorded in pre-designed data collection sheet. Result: A total number of 60 were recruited in this study. 30 were case group and 30 were control group. In our study, more than one quarter of cases (26.7%) was found between 26-30 years, while lowest age incidence was 16-20 years (6.7%). More than 37% of cases had their attack of Bell’s palsy in monsoon season, only 3% in autumn. 52.3% had pain in or around the ear. Taste abnormalities were found in 23.3%. Conclusion: From this study, it can be concluded that, Herpes simplex type 1 may be an important causative agent for Bell’s palsy. But a large scale study is needed for establishment of Herpes Simplex type 1 as an important infective agent for causation of Bell’s palsy. Bangladesh Journal of Neuroscience 2016; Vol. 32 (1): 12-15

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1型单纯疱疹病毒感染与贝尔氏麻痹的关系

背景:特发性面瘫是神经学实践中最常见的疾病之一。目的:观察贝尔麻痹是否与单纯疱疹病毒1型血清学标志物相关，研究贝尔麻痹的临床体征和症状。方法:回顾性观察研究于2014年6月至2016年5月在达卡ShSMCH神经内科门诊进行。所有到门诊就诊的患者被选为研究人群。所有符合纳入标准的相关数据均记录在预先设计的数据收集表中。结果:本研究共招募60人。病例组30例，对照组30例。在我们的研究中，超过四分之一的病例(26.7%)发生在26-30岁之间，而最低的发病率是16-20岁(6.7%)。超过37%的贝尔麻痹病例发生在季风季节，只有3%发生在秋季。52.3%的人有耳内或耳周疼痛。味觉异常占23.3%。结论:1型单纯疱疹可能是贝尔氏麻痹的重要致病因子。但要证实1型单纯疱疹病毒是引起贝尔麻痹的重要感染因子，还需要进行大规模的研究。孟加拉国神经科学杂志2016;Vol. 32 (1): 12-15

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Bangladesh Journal of Neuroscience

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