Effects of microencapsulation on antifungal activity of bombana clove oil (Syzigium aromaticum L.) against Candida albicans

Abstract

Clove oil microencapsulated with maltodextrin as an antifungal agent against Candida albicans could produce different clear zones. A ratio of clove oil to maltodextrin of 1: 4 yielded clear zones in the medium group. Meanwhile, other ratios of 1: 6, 1: 8, 1:10, and 1:12, including the antifungal properties of clove oil, yielded clear zones in the strong category. The one-way ANOVA test results showed Fscore = 22.56 > Ftab(α = 0.01) = 5.06; indicating that at least one average clear zone diameter differed significantly from those of other treatment groups. HSD test shows that ratios of 1: 4 and 1: 6 obtained |Yi−Yj| > HSD, meaning that the coating has a negative effect. Meanwhile, in the ratios of 1:8; 1:10, and 1:12, the HSD test showed that |Yi−Yj| < HSD, meaning that the presence of maltodextrin did not affect. The increase in coating material was suspected to result in a more extensive distribution of clove oil in the coating material, thus increasing the interaction with Candida albicans.