{"title":"Hemophagocytic lymphohistiocytosis associated with severe P. falciparum malaria – A case report","authors":"Vikram Bhaskar , Shilpa Devamare , Suvasini Sharma , Sunita Sharma , Jagdish Chandra","doi":"10.1016/j.pid.2016.06.011","DOIUrl":null,"url":null,"abstract":"<div><p><span><span>Hemophagocytic lymphohistiocytosis (HLH) has been associated with infections, </span>hematological malignancies<span> and autoimmune conditions. Malaria has been rarely reported as a cause of HLH, and even rarer in pediatric population. We report a case of 10-year-old female child with fever, hepatospenomegaly, </span></span>pancytopenia<span><span>, hyperferritinemia, </span>hypertriglyceridemia<span> and bone marrow hemophagocytosis, favoring the diagnosis of HLH. She required steroid administration for clinical remission.</span></span></p></div>","PeriodicalId":19984,"journal":{"name":"Pediatric Infectious Disease","volume":"8 4","pages":"Pages 115-117"},"PeriodicalIF":0.0000,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.pid.2016.06.011","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric Infectious Disease","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212832816300352","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Hemophagocytic lymphohistiocytosis (HLH) has been associated with infections, hematological malignancies and autoimmune conditions. Malaria has been rarely reported as a cause of HLH, and even rarer in pediatric population. We report a case of 10-year-old female child with fever, hepatospenomegaly, pancytopenia, hyperferritinemia, hypertriglyceridemia and bone marrow hemophagocytosis, favoring the diagnosis of HLH. She required steroid administration for clinical remission.
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