Migration of Gentamicin Beads into Duodenum following Treatment of Primary Infection of the Aorta

D.R. Robinson , H. Kanhere , B. George , G.L. Benveniste
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Abstract

Introduction

Gentamicin impregnated beads have been used in the treatment and prevention of infections in vascular surgery.

Report

A patient presented with sepsis 6 years after repair of an infrarenal aortic mycotic aneurysm with an in situ polytetrafluoroethylene (PTFE) graft and implanted gentamicin beads. Several beads migrated into the duodenum resulting in a paraprosthetic sinus. The patient was successfully treated with duodenal resection and Roux-en-Y anastomosis.

Discussion

This report highlights a serious complication relating to the implantation of gentamicin beads in the retroperitoneum. We would advocate aggressive debridement and coverage of the infected field with well-vascularised tissue rather than permanent gentamicin bead implantation.

原发主动脉感染治疗后庆大霉素微粒进入十二指肠的迁移
前言:庆大霉素浸渍微珠已被用于血管外科手术感染的治疗和预防。报告1例患者在原位聚四氟乙烯(PTFE)移植物和植入庆大霉素珠修复肾下主动脉真菌性动脉瘤6年后出现败血症。几个小珠迁移到十二指肠,形成假体旁窦。患者经十二指肠切除术及Roux-en-Y吻合术治疗成功。本报告强调了与在腹膜后植入庆大霉素珠有关的严重并发症。我们提倡积极清创,用血管良好的组织覆盖感染区,而不是永久植入庆大霉素头。
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