Active targeting of rhenium (iv) oxide (ReO2), rhenium trioxide (ReO3) and rhenium (vii) oxide (Re2O7) nanoparticles as cancer therapeutics swell-up to kill cancer cells under synchrotron and synchrocyclotron radiations

Alireza Heidari, Margaret Hotz, Nancy MacDonald, Victoria Peterson, Angela Caissutti, E. Besana, J. Esposito, K. Schmitt, Ling-Yu Chan, Francesca Sherwood, M. Henderson, Jimmy Kimmel
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引用次数: 7

Abstract

In the current research, active targeting of Rhenium (IV) Oxide (ReO2), Rhenium Trioxide (ReO3) and Rhenium (VII) Oxide (Re2O7) nanoparticles as cancer therapeutics swell–up to kill cancer cells under synchrotron and synchrocyclotron radiations is investigated. The calculation of thickness and optical constants of Rhenium (IV) Oxide (ReO2), Rhenium Trioxide (ReO3) and Rhenium (VII) Oxide (Re2O7) active targeting of Rhenium (IV) Oxide (ReO2), Rhenium Trioxide (ReO3) and Rhenium (VII) Oxide (Re2O7) nanoparticles as cancer therapeutics swell–up to kill cancer cells under synchrotron and synchrocyclotron radiations produced using sol–gel method over glassy medium through a single reflection spectrum is presented. To obtain an appropriate fit for reflection spectrum, the classic Drude–Lorentz model for parametric di–electric function is used. The best fitting parameters are determined to simulate the reflection spectrum using Lovenberg–Marquardt optimization method. The simulated reflectivity from the derived optical constants and thickness are in good agreement with experimental results.   Active targeting of Rhenium (IV) Oxide (ReO2), Rhenium Trioxide (ReO3) and Rhenium (VII) Oxide (Re2O7) nanoparticles as cancer therapeutics swell–up to kill cancer cells under synchrotron and synchrocyclotron radiations.  
主动靶向氧化铼(ReO2)、三氧化铼(ReO3)和氧化铼(Re2O7)纳米粒子作为癌症治疗药物在同步加速器和同步回旋加速器辐射下膨胀杀死癌细胞
在同步加速器和同步回旋辐射下,研究了氧化铼(ReO2)、三氧化铼(ReO3)和氧化铼(VII)纳米颗粒作为肿瘤治疗药物的活性靶向性,以杀死癌细胞。本文通过单反射光谱计算了在玻璃介质上采用溶胶-凝胶法产生的同步加速器和同步加速器辐射下氧化铼(IV)氧化物(ReO2)、三氧化铼(ReO3)和氧化铼(VII)氧化物(Re2O7)纳米粒子作为肿瘤治疗药物膨胀杀死癌细胞的厚度和光学常数。为了得到反射谱的合适拟合,采用了参数双电函数的经典德鲁德-洛伦兹模型。利用Lovenberg-Marquardt优化方法确定了模拟反射光谱的最佳拟合参数。由光学常数和厚度计算得到的反射率与实验结果吻合较好。在同步加速器和同步回旋加速器辐射下,氧化铼(IV)、三氧化铼(ReO3)和氧化铼(VII)纳米粒子作为癌症治疗药物膨胀杀死癌细胞。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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