Is Nanoparticle Efficacy is a Function of Surface Area

Abstract

In the 21st Century, human has made an enormous advance in the field of science particularly in the area of nanotechnology and finds wide application in the fields of environmental protection, hygiene, therapy, and agriculture due to the high efficacy of nanoparticle. But the actual reason for the higher efficacy of nanoparticle is yet not clear in the true sense. Researchers consider that the nanoparticles show higher efficacy/toxicity due to their large surface area. But on the other side, the researcher also reported that non-spherical nanoparticles also shown the same or some times higher toxicity or efficacy than spherical nanoparticles. Therefore, this hypothesis is made to explain; why some times non-spherical nanoparticles show the same or higher efficacy/toxicity instead of having low surface area than a spherical nanoparticle.