Primary Headache Disorders in HIV-Infected Patients within a Hospital Setting in Sub-Saharan Africa, Benin Case: Prevalence and Associated Factors

D. Gnonlonfoun, M. Agbétou, A. Wanvoegbe, C. Adjien, R. Gnimavo, A. Sowanou, R. Domingo, Joseph Adoco, D. Zannou, D. Houinato
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Abstract

Introduction: Headache disorders are common in HIV-infected patients. These disorders are either primary or secondary. Objective: Determine prevalence and factors associated with primary headache disorders in HIV+ patients. Method: It was a cross-sectional, descriptive and analytical study conducted from 2nd May 2017 to 2nd August 2017 which included HIV+ patients aged 18 years and above. Diagnosis of primary headache disorders was carried out by a Neurologist on the basis of ICHD-II diagnostic criteria. The dependent variable was primary headache disorders. Epi Info Version 7.2.1.0 and STATA11 were used for data analysis. P Results: Primary headache disorders prevalence was 25.2% (124/493).Tension-type headache represented 77.41%. HIV+ patients were aged 42.63 ± 10.14 years. Sex-ratio was estimated at 0.14. Factors associated with primary headache disorders in HIV+ patients were: male (0.36 [0.17 - 0.77]; P = 0.008), Dendi ethnicity (14.8 [2.08 - 101.99]; P = 0.007), trader (3.09 [01.25 - 7.62]; P = 0.02), WHO clinical stage (3.20 [1.43 - 7.17]; P = 0.005), screening duration (1.01 [1.00 - 1.01]; P = 0.00), hypertension (10.28 [4.44 - 23.83]; P ≤ 0.001). Conclusion: This study helped to determine the standard profile of HIV+ patient with primary headache disorders. It will contribute to save costs associated with paraclinical examinations, while in search of secondary etiologies within an African context with limited financial resources.
在撒哈拉以南非洲的医院环境中,贝宁病例中hiv感染患者的原发性头痛疾病:患病率和相关因素
导言:头痛疾病在hiv感染患者中很常见。这些疾病有的是原发的,有的是继发的。目的:确定HIV+患者原发性头痛疾病的患病率及相关因素。方法:于2017年5月2日至2017年8月2日进行横断面、描述性和分析性研究,纳入18岁及以上HIV阳性患者。原发性头痛疾病的诊断由神经科医生根据ICHD-II诊断标准进行。因变量为原发性头痛疾病。使用Epi Info Version 7.2.1.0和STATA11进行数据分析。结果:原发性头痛疾病患病率为25.2%(124/493)。紧张性头痛占77.41%。HIV阳性患者年龄42.63±10.14岁。性别比估计为0.14。与HIV阳性患者原发性头痛疾病相关的因素有:男性(0.36 [0.17 - 0.77];P = 0.008), Dendi族(14.8 [2.08 - 101.99];P = 0.007),交易员(3.09 [01.25 - 7.62];P = 0.02), WHO临床分期(3.20 [1.43 - 7.17];P = 0.005)、筛查时间(1.01 [1.00 - 1.01];P = 0.00),高血压(10.28 [4.44 - 23.83];P≤0.001)。结论:本研究有助于确定HIV阳性患者原发性头痛疾病的标准概况。它将有助于节省与临床旁检查相关的费用,同时在财政资源有限的非洲背景下寻找继发性病因。
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