John G. Lindberg and the discovery of exfoliation syndrome.

A. Tarkkanen, T. Kivelä
{"title":"John G. Lindberg and the discovery of exfoliation syndrome.","authors":"A. Tarkkanen, T. Kivelä","doi":"10.1034/J.1600-0420.2002.800206.X","DOIUrl":null,"url":null,"abstract":"John G. Lindberg, a young Finnish ophthalmology resident, started a research project in 1914 aiming at an academic dissertation. His plan was to elucidate Axenfeld's observations on iris changes in senile eyes. Axenfeld had described two types of degeneration of the iris: a hyaline degeneration of the iris pupillary zone causing poor pupillary dilatation with mydriatics and an atrophy of the iris pigment epithelium at the pupillary border. For his research Lindberg had to construct a slit-lamp biomicroscope by studying Gullstrand's monograph on the matter; slit-lamp biomicroscopes were not commercially available at that time. A Sach's lamp was used for transillumination of the iris. While conducting his research Lindberg paid attention to greyish flakes and fringes at the pupillary border. He also noted how this strange material formed a membrane on the anterior lens surface. Documentation was made by skillful hand drawings. The new phenomenon was found to be as common in cataract patients as in non-cataractous controls older than 55 years. The phenomenon was observed in 50% of glaucoma patients. Age was the decisive factor; the phenomenon was more prevalent with advancing age. Lindberg published his results as a thesis at the University of Helsinki in 1917. When attending a Nordic Congress of Ophthalmology in 1921, Lindberg met Norwegian ophthalmologist, Birger Malling, and gave him his thesis and explained the new findings. In 1920-21 Lindberg worked at Axenfeld's clinic in Freiburg, Germany. During this period he met in Basel, Switzerland, a Swiss ophthalmologist, Alfred Vogt. He told Vogt about his research and provided him with copies of his thesis. Both Malling and Vogt published papers on exfoliation in 1923 without referring to Lindberg's work. Lindberg did not, however, interfere with these papers. Thus Lindberg was forgotten by his contemporaries as a scientist. However, his main conclusions on exfoliation are still valid today. The life of this remarkable ophthalmologist is described in the present paper.","PeriodicalId":7152,"journal":{"name":"Acta ophthalmologica Scandinavica","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2002-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"40","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta ophthalmologica Scandinavica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1034/J.1600-0420.2002.800206.X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 40

Abstract

John G. Lindberg, a young Finnish ophthalmology resident, started a research project in 1914 aiming at an academic dissertation. His plan was to elucidate Axenfeld's observations on iris changes in senile eyes. Axenfeld had described two types of degeneration of the iris: a hyaline degeneration of the iris pupillary zone causing poor pupillary dilatation with mydriatics and an atrophy of the iris pigment epithelium at the pupillary border. For his research Lindberg had to construct a slit-lamp biomicroscope by studying Gullstrand's monograph on the matter; slit-lamp biomicroscopes were not commercially available at that time. A Sach's lamp was used for transillumination of the iris. While conducting his research Lindberg paid attention to greyish flakes and fringes at the pupillary border. He also noted how this strange material formed a membrane on the anterior lens surface. Documentation was made by skillful hand drawings. The new phenomenon was found to be as common in cataract patients as in non-cataractous controls older than 55 years. The phenomenon was observed in 50% of glaucoma patients. Age was the decisive factor; the phenomenon was more prevalent with advancing age. Lindberg published his results as a thesis at the University of Helsinki in 1917. When attending a Nordic Congress of Ophthalmology in 1921, Lindberg met Norwegian ophthalmologist, Birger Malling, and gave him his thesis and explained the new findings. In 1920-21 Lindberg worked at Axenfeld's clinic in Freiburg, Germany. During this period he met in Basel, Switzerland, a Swiss ophthalmologist, Alfred Vogt. He told Vogt about his research and provided him with copies of his thesis. Both Malling and Vogt published papers on exfoliation in 1923 without referring to Lindberg's work. Lindberg did not, however, interfere with these papers. Thus Lindberg was forgotten by his contemporaries as a scientist. However, his main conclusions on exfoliation are still valid today. The life of this remarkable ophthalmologist is described in the present paper.
约翰·g·林德伯格和脱落综合症的发现。
年轻的芬兰眼科住院医生约翰·g·林德伯格(John G. Lindberg)在1914年开始了一项研究项目,目的是写一篇学术论文。他的计划是阐明阿森菲尔德对老年眼睛虹膜变化的观察。Axenfeld描述了两种类型的虹膜变性:虹膜瞳孔区透明变性导致瞳孔扩张不良伴瞳孔散瞳,以及虹膜瞳孔边界色素上皮萎缩。为了他的研究,Lindberg必须通过研究Gullstrand关于这个问题的专著来构建一个裂隙灯生物显微镜;当时,裂隙灯生物显微镜还没有商业化。用萨氏灯透视虹膜。在进行他的研究时,林德伯格注意到了瞳孔边缘的灰色薄片和条纹。他还注意到这种奇怪的物质是如何在前晶状体表面形成膜的。文件是由熟练的手绘出来的。这种新现象在55岁以上的白内障患者和非白内障对照组中同样普遍。50%的青光眼患者有此现象。年龄是决定性因素;随着年龄的增长,这种现象更为普遍。林德伯格于1917年在赫尔辛基大学发表了他的论文。在1921年参加北欧眼科大会时,Lindberg遇到了挪威眼科医生Birger Malling,并将他的论文交给了他,并解释了他的新发现。1920年至1921年,林德伯格在德国弗莱堡的阿森菲尔德诊所工作。在此期间,他在瑞士巴塞尔遇到了瑞士眼科医生阿尔弗雷德·沃格特。他把自己的研究告诉了沃格特,并给他提供了论文的副本。莫林和沃格特都在1923年发表了关于去角质的论文,但没有提及林德伯格的工作。然而,林德伯格并没有干涉这些论文。因此,林德伯格作为一名科学家被他的同时代人所遗忘。然而,他关于去角质的主要结论今天仍然有效。本文描述了这位杰出的眼科医生的生活。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信