Insilico pharmacological evaluation of dibenzosuberenone derivatives as antidepressant

S. A, Umarani G, Tamilarasi G, Senthilkumar R, M. K
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Abstract

A new drug takes a long time and is expensive to introduce.By using insilico drug design, you can save time and money. Utilizing computational software, a novel Schiff's base Dibenzosuberenone derivative was designed and molecular docking studies were performed using autodock software. To predict Absorption, Distribution, Metabolism, Excretion, and Molecular Properties of Dibenzosuberenone derivatives, insilico screening was performed. It should be examined how its Dibenzosuberenone derivatives interact with specific targets. The Dibenzosuberenone derivatives were successfully identified as targets in this study.
二苯并亚苯酮衍生物抗抑郁药物的体外药理评价
一种新药需要很长时间,而且引进成本很高。通过使用计算机药物设计,您可以节省时间和金钱。利用计算软件,设计了一种新型希夫碱二苯并醌衍生物,并使用autodock软件进行了分子对接研究。为了预测二苯并亚烯酮衍生物的吸收、分布、代谢、排泄和分子性质,进行了硅筛选。应该研究其二苯并酮衍生物如何与特定靶标相互作用。本研究成功地鉴定了二苯并醌衍生物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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