Dual intracranial primaries: A rare occurrence

Abstract

The incidence of two or more intracranial malignancies of different cell types is extremely rare with an incidence of <0.9% of all primary central nervous system tumors. Herein, we report the rare combination of pituitary macroadenoma, benign condition with glioblastoma multiforme, highly aggressive malignancy in a 33-year-old male with the initial complaints of intermittent headache and vomiting. The clinical presentation, radiological characteristics, and treatments received by the patient are briefly discussed along with review of literature. The patient was treated with surgery followed by chemoradiotherapy and medical management. Post radiation, contrast-enhanced computed tomography scan of the brain showed postoperative changes with the resolution of the pituitary lesion.