Anti-wrinkle and Moisturizing Activity of Echinacea angustifolia Extract as a Cosmetic ingredient

Abstract

Purpose: Echinacea angustifolia (E. angustifolia) extract’s usefulness as a cosmetic ingredient was examined. This study confirmed its skin improvement effects through a moisturizing and elasticity test and clinical trials.Methods: Cell ability of E. angustifolia on HaCaT and CCD986sk cells was measured by MTT assay respectively. And hyaluronic acid in HaCaT cells and pro-collagen acid productions in CCD986sk cells were measured.Results: As a result of the cytotoxicity test on CCD986sk and HaCaT cells, it was confirmed that there was no cytotoxicity at a concentration of 200 μg/mL or less. At a concentration of 200 μg/mL, both hyaluronic acid and collagen productions showed statistically significant differences. Meanwhile, the skin improvement test performed in the clinical trials revealed high scores compared to a control group and a significant difference was observed especially in moisturizing and wrinkle-care effects (p <0.001, p <0.01).Conclusion: With the potential of E. angustifolia extract, this study confirmed its promise as a cosmeceutical cosmetics ingredient.