Chronic hypoparathyroidism after thyroid surgery: Benefits of specialized and personalized care in a tertiary public hospital

M. Tavares, F. Vanderlei, M. Teixeira, D. A. Rocha, S. Serrano, Luis Felipe de Barros Ura, R. Moyses
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Abstract

Financial support: None. Conflicts of interest: No conflicts of interest declared concerning the publication of this article. Submitted: June 24, 2019. Accepted: October 01, 2019. The study was carried out at Serviço de Cirurgia de Cabeça e Pescoço, Faculdade de Medicina, Hospital das Clínicas, Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brasil. Article presented at the XXVII Congresso Brasileiro de Cirurgia de Cabeça e Pescoço, in August 2019 Abstract Introduction: As the number of thyroid operations increases, the incidence of complications also increases, including transitory and definite hypoparathyroidism. Since each patient presents different and unpredictable symptoms, affecting several organs and systems, they need personalized care. Even when patients presented with low calcium blood levels, the previous results were considered acceptable, usually using oral prescriptions of calcium carbonate and calcitriol. We created in March 2017 a specialized outpatient treatment facility for those patients focused on generating experience and knowledge about hypoparathyroidism. Objective: To analyze the challenges and the impact of specialized care in diagnosis, treatment and in follow-up of patients with postoperative hypoparathyroidism, with potential to improve teaching and further research possibilities in the subject. Methods: 61 patients were studied: 55 women, age 18-55. A retrospective study was performed, considering specialized guidelines. We also analyzed blood levels of calcium, parathyroid hormone, vitamin D, and other minerals; kidney function; bone structure. Results: Some patients needed drug dose adjustments up to 66%. We were able to identify kidney structural and functional changes. We could share those experiences in a multidisciplinary way, contributing significantly to provide more experience to the medical residents. Conclusion: Specialized outpatient treatment is responsible for providing more efficient and safe treatment to the patients, and it is also important to enable further medical research.
甲状腺手术后慢性甲状旁腺功能减退:三级公立医院专业化和个性化护理的益处
资金支持:无。利益冲突:本文发表未声明存在利益冲突。提交日期:2019年6月24日。录用日期:2019年10月1日。这项研究是在巴西圣保罗州圣保罗市圣保罗市圣保罗大学(HC-FMUSP) 医学院、圣保罗市医学院、圣保罗市医院Clínicas进行的。摘要简介:随着甲状腺手术数量的增加,并发症的发生率也在增加,包括短暂性和明确的甲状旁腺功能减退。由于每个病人表现出不同的和不可预测的症状,影响到几个器官和系统,他们需要个性化的护理。即使患者出现低血钙水平,以前的结果也被认为是可以接受的,通常使用碳酸钙和骨化三醇口服处方。我们于2017年3月为这些患者创建了一个专门的门诊治疗设施,专注于提供有关甲状旁腺功能减退的经验和知识。目的:分析专科护理在甲状旁腺功能减退术后患者的诊断、治疗和随访中所面临的挑战和影响,为改进该学科的教学和进一步研究提供可能。方法:对61例患者进行研究:女性55例,年龄18 ~ 55岁。考虑到专门的指导方针,进行了回顾性研究。我们还分析了血液中钙、甲状旁腺激素、维生素D和其他矿物质的水平;肾脏功能;骨结构。结果:部分患者需要调整药物剂量达66%。我们能够确定肾脏的结构和功能变化。我们可以以多学科的方式分享这些经验,为住院医生提供更多的经验做出重大贡献。结论:专科门诊为患者提供更高效、更安全的治疗,对进一步开展医学研究具有重要意义。
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