Important about the Manipulations of the Pharmaceutical Concerns, the OSMS (One Step Melanoma Surgery) and the Drug Induced Melanoma: "You Dream Things; You Say, 'Why?' But I See Things Before My Eyes; And I Say ‘Why Not?’"

G. Tchernev, I. Temelkova
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Abstract

Approach variability in melanoma surgery is more likely to be artificially created and refers mainly to: 1) the surgical safety margins; 2) the clinician’s compliance with the patient’s choice to pre-define these margins for a better cosmetic outcome; 3) the interval within which re-excisions may be carried out; 4)discrepancy between the clinically respected and histologically established tumor resection margins; 5)as well as the lack of additional guidelines for re-excisions within the already established differences between the clinically and histologically established resection margin. These ʺinaccuraciesʺ make it difficult to implement the current guidelines and often lead to confusion. We assume that the approach variability is for sure not established and based only on the opinion of the so-called ‘expert groups’!
重要的是对药物问题的操纵,OSMS(一步黑色素瘤手术)和药物诱导的黑色素瘤:“你做梦;你说:“为什么?”但我看到眼前的东西;我说‘为什么不呢?’”
黑色素瘤手术的入路可变性更有可能是人为造成的,主要指:1)手术安全界限;2)临床医生是否遵从患者的选择,预先定义这些边缘,以获得更好的美容效果;3)可再次切除的时间间隔;4)临床判断的肿瘤切除边缘与组织学确定的肿瘤切除边缘存在差异;5)以及缺乏在临床和组织学上已经确定的切除边缘之间的差异范围内再切除的额外指南。这些“不准确性”使得目前的指导方针难以实施,并经常导致混乱。我们假设方法的可变性肯定不是建立的,只是基于所谓的“专家组”的意见!
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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