Ultrasonic extraction of ferulic acid from Ligusticum chuanxiong

Journal of The Chinese Institute of Chemical Engineers Pub Date : 2008-11-01 DOI:10.1016/j.jcice.2008.05.012

Yongyue Sun , Wenhua Wang

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引用次数: 28

Abstract

The extraction of ferulic acid, a pharmacologically active ingredient from the root of Ligusticum chuanxiong, with ultrasonic extraction was investigated. Percolation and supercritical fluid extraction (SFE) were employed to make comparisons with ultrasonic extraction. Three variables, which included the concentration of solvent, the ratio of solvent volume/sample (mL/g), and extraction time, were found to have a great influence on ultrasonic extraction. The optimum extraction was with pure ethanol with a solvent volume/sample ratio 8:1 (mL/g) and extraction time of 30 min. Under the optimum extraction conditions, the extraction yield could reach 8.8% which was higher than that using SFE with ethanol as co-solvent and a content of ferulic acid of 0.7%; both the yield and the content were higher than those obtained by percolation. Ultrasonic extraction significantly shortened the time required for the extraction process. Overall, ultrasonic extraction was shown to be highly efficient in the extraction of ferulic acid from Ligusticum chuanxiong.

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超声波提取川芎中阿魏酸的研究

研究了超声波提取川芎根中有效成分阿魏酸的工艺。采用渗流法和超临界流体萃取法(SFE)与超声波萃取法进行了比较。溶剂浓度、溶剂体积/样品比(mL/g)和提取时间对超声提取有较大影响。最佳提取条件为纯乙醇，溶剂体积比为8:1 (mL/g)，提取时间为30 min。在最佳提取条件下，阿魏酸的提取率可达8.8%，高于以乙醇为助溶剂、阿魏酸含量为0.7%的SFE;收率和含量均高于渗滤法。超声提取显著缩短了提取过程所需的时间。综上所述，超声波提取川芎中阿魏酸是一种高效的提取方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of The Chinese Institute of Chemical Engineers

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