Dramatic Recovery of a Patient With Wernicke Encephalopathy Presenting With the Lesion of the Corpus Callosum

H. Onder
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Abstract

In this report, I present a rare patient of Wernicke encephalopathy (WE) with a callosal lesion on magnetic resonance imaging at whom a dramatic clinical recovery was achieved by parenteral thiamine therapy. Based on the presentation of this patient, first, I suggest that the awareness of WE among clinicians should be further increased. Second, I re-emphasize the importance of initiation of parenteral thiamine treatments in clinical suspicion of WE which may provide dramatic responses even in patients with atypical lesion sites as in our patient. Future reports including outcomes of a larger number of cases with distinct neuroimaging signs may provide a better understanding of the real clinical burden of the disease as well as unknown aspects of WE. J Neurol Res. 2020;10(1):17-19 doi: https://doi.org/10.14740/jnr559
一例以胼胝体病变为表现的韦尼克脑病患者的戏剧性康复
在此报告中,我报告了一位罕见的韦尼克脑病(WE)患者,磁共振成像显示胼胝体病变,经静脉注射硫胺素治疗后临床恢复明显。根据该患者的表现,首先,我建议临床医生应进一步提高对WE的认识。其次,我再次强调在临床怀疑WE时开始静脉注射硫胺素治疗的重要性,即使在像我们的患者一样具有非典型病变部位的患者中,也可能提供显着的反应。未来的报告,包括更多具有不同神经影像学征象的病例的结果,可能会更好地了解该疾病的真正临床负担以及WE的未知方面。中华神经科学杂志,2020;10(1):17-19 doi: https://doi.org/10.14740/jnr559
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