Atrophic dermatofibrosarcoma protuberans and enlargement with pregnancy: Case report and literature review

Abstract

Dermatofibrosarcoma protuberans (DFSPs) are a slowly growing locally aggressive tumor of disputed histogenesis with low-grade malignancy and a marked tendency to local recurrence but rarely metastasize to distant sites. Few reports have suggested that DFSPs may enlarge more rapidly during pregnancy. This article describes a lesion of the atrophic variant of DFSP that increased in size during pregnancy which is an unusual presentation, and a review of the literature.