Impact of Dehydrated Human Amniotic Membrane Allograft (AmnioFix®) on Continence and Potency Following Robot-Assisted Radical Prostatectomy

Journal of endourology. Part B, Videourology Pub Date : 2015-07-31 DOI:10.1089/VID.2014.0074

Anup Kumar, S. Samavedi, A. Bates, R. Coelho, B. Rocco, J. Marquinez, Ignacio Camacho, C. Jenson, K. Palmer, V. Patel

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引用次数: 2

Abstract

Abstract Introduction and Objectives: Allografts of dehydrated human amniotic membrane (dHAM) have cytokines and growth factors that have been shown to reduce the inflammatory response during tissue healing and promote nerve regeneration. This is the first reported study evaluating the early quality of life outcomes after placement of dHAM on the neurovascular bundle (NVB) during nerve-sparing robot-assisted radical prostatectomy (RARP). We demonstrate our technique in this video. Methods: From March 2013 to July 2014, 58 preoperatively potent (Sexual Health Inventory for Men score >19) and continent patients underwent full nerve-sparing RARP, followed by intraoperative dHAM placement at our institution. In each patient, the dHAM was wrapped around the NVB following the RARP procedure. We performed propensity matching using our prospective database in matched nongrafted patients from the same time period. Pre-, peri-, and postoperative outcomes were analyzed between patient groups, including the time to r...

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脱水人羊膜异体移植(AmnioFix®)对机器人辅助根治性前列腺切除术后尿失禁和效能的影响

摘要简介和目的:脱水人羊膜(dHAM)异体移植物含有细胞因子和生长因子，已被证明可以减少组织愈合过程中的炎症反应，促进神经再生。这是首次报道的研究，评估在神经保留机器人辅助根治性前列腺切除术(RARP)中，在神经血管束(NVB)上放置dHAM后的早期生活质量。我们在这个视频中演示我们的技术。方法:2013年3月至2014年7月，58例术前有效(男性性健康量表评分>19)和大陆患者接受了完全保留神经的RARP，术中植入dHAM。在每位患者中，按照RARP程序将dHAM包裹在NVB上。我们使用前瞻性数据库对来自同一时期的匹配的未移植患者进行倾向匹配。分析两组患者的术前、围手术期和术后结果，包括术后随访时间。

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Journal of endourology. Part B, Videourology

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