Alterations of Serum Lipids Profiles in Patients with Head and Neck Cancers

Abstract

Aim: The aim of the present study is to evaluate the alterations and clinical significance of plasma lipid profiles in untreated head and neck malignancies. Methods: The present case-control study comprises of newly diagnosed and histologically confirmed, 50 head and neck cancer cases between 2021-2022 in the Department of Otorhinolaryngology and Head and Neck Surgery, Tishreen University Hospital, Lattakia, with 25 healthy controls. Fasting blood samples were collected and the lipid profile studied and compared between groups in terms of mean and standard deviation. Results: The mean difference in the levels of total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), very-low-density lipoprotein (VLDL), and triglyceride (TGL) between the case group and control group was significant in our study, that is, these lipid parameters were significantly lower in the case group than that of the control group.