Structure of acute chemical poisoning during COVID-19 pandemic (according to a multidiscipline hospital)

A. H. Lodyagin, Andrei Georgievich Sinenchenko, V. Shilov, B. Batotsyrenov, G. Sinenchenko
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Abstract

Introduction. The article presents an epidemiological analysis of the prevalence and structure of acute chemical poisoning in the Northwestern region during the Covid-19 pandemic. The purpose of the study: to analyze the prevalence and structure of acute chemical poisoning among patients of a multidisciplinary hospital during the Covid-19 pandemic. Materials and methods. In the course of the work, archival, monthly statistical data were used on the registration of persons hospitalized in the center for the treatment of acute poisoning of the named after I.I. Dzhanelidze Research Institute of SP in the period 2019-2020. The main method of the study was clinical and epidemiological, which includes an analysis of the intra-annual dynamics of the occurrence of acute chemical poisoning, based on monthly observations. In the statistical processing of the material, numerical characteristics of variables with an assessment of their accuracy and reliability were used, analytical methods aimed at constructing a time series model by autoregression and integrated moving average (ARIMA) were used. Nominal data were compared using the criterion χ2 adjusted for continuity. Results. The epidemiological analysis revealed the main trends indicating a decrease in the total number of admissions of patients with acute chemical poisoning to a multidisciplinary hospital during the Covid-19 pandemic (y = -106.25x + 17.16, R2 = 0.7346). The data obtained indicate, first of all, a decrease in the income of persons with acute alcohol poisoning and higher alcohols, starting from April 2020, which, of course, was facilitated by the introduction of a strictly anti-epidemic regime in the GBU Research Institute of SP named after I.I. Dzhanelidze and the change in the conditions of hospitalization in medical institutions of St. Petersburg during the Covid-19 pandemic. The increase in the frequency of acute poisoning with medicinal substances (antipyretics, analgesics and sedatives) used for the purpose of self-treatment of the main symptoms of an infectious disease has attracted attention. The main problem for public health remains the increase in the number of cases of acute poisoning with narcotic substances from the group of synthetic cathinones, synthetic derivatives of opium, precursors of gamma-hydroxyoximabutyric acid. Conclusion. Data on the prevalence of acute chemical poisoning during the Covid-19 pandemic (according to the multidisciplinary hospital) indicate changes in the frequency of their occurrence and structure. An increase in cases of admission of persons with poisoning with analgesics, antipyretics, psychotropic drugs with sedative effect was found in the analyzed time period.
新冠肺炎大流行期间急性化学中毒的结构分析(以某多学科医院为例)
介绍。本文对新冠肺炎大流行期间西北地区急性化学中毒的发病情况和结构进行了流行病学分析。本研究目的:分析新冠肺炎大流行期间某多学科医院患者急性化学物质中毒的发生率和结构。材料和方法。在工作过程中,对2019-2020年期间SP . i.i.d zhanelidze研究所急性中毒治疗中心住院人员的登记使用了档案和月度统计数据。这项研究的主要方法是临床和流行病学,其中包括在每月观察的基础上分析急性化学中毒发生的年度动态。在材料的统计处理中,利用变量的数值特征及其准确性和可靠性评估,采用自回归和综合移动平均(ARIMA)的分析方法构建时间序列模型。标称资料的比较采用经连续性校正的χ2标准。结果。流行病学分析显示,疫情期间多学科医院急性化学中毒住院总人数呈下降趋势(y = -106.25x + 17.16, R2 = 0.7346)。获得的数据表明,首先,从2020年4月开始,急性酒精中毒和高酒精中毒患者的收入减少,当然,这是由于在以I.I. Dzhanelidze命名的GBU研究所引入严格的防疫制度以及在2019冠状病毒病大流行期间圣彼得堡医疗机构住院条件的变化而促成的。为自我治疗传染病的主要症状而使用药物(解热药、止痛剂和镇静剂)急性中毒的频率有所增加,这引起了人们的注意。公共卫生的主要问题仍然是,使用合成卡西酮类麻醉药品、鸦片合成衍生物、γ -羟基肟丁酸前体的急性中毒病例不断增加。结论。关于Covid-19大流行期间急性化学中毒发生率的数据(根据多学科医院)表明,其发生频率和结构发生了变化。在分析的时间段内,镇痛药、解热药和具有镇静作用的精神药物中毒患者的住院病例有所增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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