{"title":"Linaclotide for irritable bowel syndrome with constipation","authors":"Steve Chaplin MSc, MRPharmS","doi":"10.1002/fps.98","DOIUrl":null,"url":null,"abstract":"<p>Linaclotide is a guanylate cyclase agonist that promotes increased stool water content, which increases bowel movement frequency. It has recently received a positive opinion from the CHMP for the treatment of constipation-predominant IBS. In this Drug profile Steve Chaplin presents the clinical data relating to its efficacy and adverse events. Copyright © 2013 John Wiley & Sons, Ltd.</p>","PeriodicalId":100566,"journal":{"name":"Future Prescriber","volume":"13 3","pages":"14-16"},"PeriodicalIF":0.0000,"publicationDate":"2013-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/fps.98","citationCount":"13","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future Prescriber","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/fps.98","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 13
Abstract
Linaclotide is a guanylate cyclase agonist that promotes increased stool water content, which increases bowel movement frequency. It has recently received a positive opinion from the CHMP for the treatment of constipation-predominant IBS. In this Drug profile Steve Chaplin presents the clinical data relating to its efficacy and adverse events. Copyright © 2013 John Wiley & Sons, Ltd.
利那克洛肽治疗肠易激综合征伴便秘
利那洛肽是一种鸟苷酸环化酶激动剂，可促进粪便水分含量增加，从而增加排便频率。它最近获得了CHMP对治疗便秘为主的IBS的积极意见。在这篇药物简介中，Steve Chaplin介绍了有关其疗效和不良事件的临床数据。版权所有©2013 John Wiley &儿子,有限公司
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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