Restoration Of Left Ventricular Function Following LVAD Implantation – Remission Or Recovery? A Case series

S. Joshi, Mariah Barlow, M. Guglin
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Abstract

Background A wide range of left ventricular (LV) recovery rates on left ventricular assist device (LVAD) support have been reported. In this case series, we summarize our experience with LVAD explantation for presumed LV recovery. Case series Out of 240 patients who received an LVAD implant in our program since its inception, we explanted/inactivated the pump for presumed LV recovery in only three patients. All three of these patients had relapse of cardiomyopathy within 6 months of explantation. Conclusion Our experience does not support the existence of LV recovery following LVAD implantation as a common phenomenon. Improvement in LV function on LVAD is sustainable only with mechanical circulatory support and once the offloading support provided by the device is removed recurrent failure quickly ensue. Likely the term “remission” reflects the status more accurately than the term “recovery”.
左室辅助装置植入后左心室功能的恢复-缓解还是恢复?案例系列
背景:在左心室辅助装置(LVAD)支持下,左心室(LV)恢复率有很大范围的报道。在这个病例系列中,我们总结了我们在假定的左室恢复中使用左室辅助装置的经验。在我们项目开始以来接受左室辅助器植入的240例患者中,我们仅在3例患者中为假定的左室恢复取出/停用了泵。这3例患者均在移植后6个月内心肌病复发。结论我们的经验不支持LVAD植入后左室恢复是一种普遍现象。LVAD上左室功能的改善只有在机械循环支持下才能持续,一旦设备提供的卸载支持被移除,就会迅速出现复发性故障。“缓解”一词可能比“恢复”一词更准确地反映了这种状态。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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