A rapid determination of metallothionein in animal tissues by the Cd-Chelex method

Abstract

Determination of metallothionein (MT) by the Cd-Chelex method was investigated using dry Chelex, and the Cd-Chelex and Cd-hem methods were compared for the estimation of MT from the brain, heart, lung, liver, kidney, spleen, and testis of rats injected with CdCl2. There was in relatively good agreement between these two methods on the determination of the tissues MT containing Zn and Cd.