Détresses respiratoires du nouveau-né (en dehors des malformations et des maladies génétiques ou constitutionnelles)

S Lorotte-Namouni (Chef de clinique-assistante des hôpitaux de Paris) , C Clamadieu (Praticien hospitalier) , P.-H Jarreau (Professeur des Universités, praticien hospitalier)
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引用次数: 10

Abstract

Respiratory disorders are one of the main cause of neonatal morbidity and mortality. Their aetiology is predominantly linked to an inappropriate cardio-respiratory adaptation at birth and to infections. Recent improvements in the management of these disorders diminished dramatically the mortality. These improvements are due to a better perinatal care organization, and to substantial advances in obstetrics and paediatrics, among which a wide use of antenatal steroids, exogenous surfactants and improvements in mechanical ventilation. Nevertheless, bronchopulmonary dysplasia remains a major problem in the outcome of the most preterm infants. A better knowledge of its physiopathology may open new therapeutic advances.

新生儿呼吸窘迫(畸形、遗传或体质疾病除外)
呼吸系统疾病是新生儿发病和死亡的主要原因之一。其病因主要与出生时不适当的心肺适应和感染有关。最近在这些疾病管理方面的改进大大降低了死亡率。这些改善是由于更好的围产期护理组织,以及产科和儿科的实质性进展,其中产前类固醇、外源性表面活性剂的广泛使用和机械通气的改进。然而,支气管肺发育不良仍然是大多数早产儿预后的主要问题。更好地了解其生理病理可能会带来新的治疗进展。
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