The reaction of curcumin-hydrazine and its effect on bone marrow mesenchymal stem cells

Abstract

In this work, the interaction between curcumin and hydrazine was studied in three different conditions: In the presence of ultrasonic waves, in the absence of ultrasonic waves, and while refluxing and the effects of the produced materials on the livability of bone marrow mesenchymal stem cells were investigated. Various methods including FT-IR, 1H NMR and 13C NMR were utilized to characterize the material. The results revealed that cell treatments with 40 μM dose of all three samples after 24 h were caused to the more biological ability of rat bone marrow mesenchymal stem cells (MSCs). This indicated that these compounds (curcumin-hydrazine) are effective in the livability of bone marrow mesenchymal stem cells (MSCs).