Hantavirus Diseases – A Comprehensive Review

IF 0.1 4区 医学 Q4 INFECTIOUS DISEASES
K. Sagadevan, B. Nandagopal, Mageshbabu Ramamurthy, N. Saravanan, P. Rajendiran, H. Narayanan, Kumaran Vadivel
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引用次数: 0

Abstract

Hantaviruses are a diverse group of infectious agents which are zoonotic in nature and transmitted to humans through rodent reservoir. Hantaviruses are enveloped RNA viruses that persistently infect rodent hosts without ill-effect. The host persistently excretes virus in urine and saliva. Man becomes infected from the rodents when one enters the ecological niche of the other. Hantaviruses can cause two types of diseases in humans: hemorrhagic fever with renal syndrome (HFRS) and Hantavirus cardiopulmonary syndrome (HCPS). The number of reported Hantavirus infections is increasing worldwide, and new Hantaviruses are being discovered in many countries, making them a global public health concern. Hantavirus infections are thought to be under diagnosed due to the fact that they frequently cause asymptomatic and nonspecific mild infections, as well as a lack of simple standardized diagnostic laboratory methods. This review summarizes current knowledge on Hantaviral infections, including virology, epidemiology, clinical manifestations, laboratory diagnostics, treatment, and prevention.
汉坦病毒疾病综述
汉坦病毒是一种具有人畜共患性质并通过啮齿动物宿主传播给人类的多种传染性病原体。汉坦病毒是一种包膜RNA病毒,可持续感染啮齿动物宿主而无不良反应。宿主持续通过尿液和唾液排出病毒。当一个人进入另一个人的生态位时,就会被啮齿动物感染。汉坦病毒可在人类中引起两种疾病:肾综合征出血热(HFRS)和汉坦病毒心肺综合征(HCPS)。世界范围内报告的汉坦病毒感染人数正在增加,许多国家正在发现新的汉坦病毒,使其成为全球公共卫生关注的问题。汉坦病毒感染被认为诊断不足,因为它们经常引起无症状和非特异性轻度感染,以及缺乏简单的标准化诊断实验室方法。本文综述了汉坦病毒感染的最新知识,包括病毒学、流行病学、临床表现、实验室诊断、治疗和预防。
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来源期刊
Southeast Asian Journal of Tropical Medicine and Public Health
Southeast Asian Journal of Tropical Medicine and Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-INFECTIOUS DISEASES
CiteScore
0.40
自引率
0.00%
发文量
0
审稿时长
3-8 weeks
期刊介绍: The SEAMEO* Regional Tropical Medicine and Public Health Project was established in 1967 to help improve the health and standard of living of the peoples of Southeast Asia by pooling manpower resources of the participating SEAMEO member countries in a cooperative endeavor to develop and upgrade the research and training capabilities of the existing facilities in these countries. By promoting effective regional cooperation among the participating national centers, it is hoped to minimize waste in duplication of programs and activities. In 1992 the Project was renamed the SEAMEO Regional Tropical Medicine and Public Health Network.
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