A Case of Pulmonary Cryptococcosis with Normal Immune Function

Xiuzhi Shi, Hua Ke, Jien-Wei Liu, Xiaohong Cao
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Abstract

Objective Pulmonary cryptococcosis (PC) is a pulmonary fungal disease caused by Cryptococcus neoformans infection, the clinical manifestations are pneumonia or pulmonary nodules, or acute respiratory distress syndrome (ARDS) in severe cases. But its clinical manifestations lack specificity, so it is often misdiagnosed or missed in recent years. Pulmonary cryptococcosis is common in patients with human immunodeficiency virus (HIV) and non-HIV-associated immunosuppression, it has been found that pulmonary cryptococcosis is also common in people with sound immune function. The purpose of this paper is to report the diagnosis and treatment process of a patient with pulmonary cryptococcosis in our hospital, so as to provide reference for the diagnosis and treatment of the disease and reduce the misdiagnosis rate and missed diagnosis rate of the disease. Methods The diagnosis and treatment process of a case of pulmonary cryptococcosis in our hospital were reviewed. Results Combined with the patient's lung CT Imaging manifestations, and environmental exposure history and immune status, pulmonary cryptococcosis was considered. After empirical anti-cryptococcosis treatment, the patient's symptoms improved, and pulmonary nodules disappeared according to lung CT review. Conclusion Clinicians should identify the imaging characteristics of patients with cryptococcus pneumonicum and combine them with their environmental exposure history and immune status to avoid missed diagnosis and delayed disease.
免疫功能正常的肺隐球菌病1例
目的肺隐球菌病是一种由新型隐球菌感染引起的肺部真菌疾病,临床表现为肺炎或肺结节,严重者可出现急性呼吸窘迫综合征(ARDS)。但其临床表现缺乏特异性,近年来常被误诊或漏诊。肺隐球菌病常见于人类免疫缺陷病毒(HIV)和非HIV相关免疫抑制患者,已发现肺隐球菌病也常见于免疫功能健全的人群。本文旨在报道我院1例肺隐球菌病患者的诊治过程,以期为该病的诊治提供参考,降低该病的误诊率和漏诊率。方法回顾我院收治的1例肺隐球菌病的诊治过程。结果结合患者肺部CT影像学表现、环境暴露史及免疫状况,考虑肺隐球菌病。经经验性抗隐球菌治疗后,患者症状好转,肺部CT复查显示肺结节消失。结论临床医生应明确肺炎隐球菌患者的影像学特征,并结合患者的环境暴露史和免疫状况,避免漏诊和延迟发病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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