Helicobacter pylori virulence factors and host genetic polymorphisms in a low gastric cancer incidence and high H pylori prevalence country

Abstract

Helicobacter pylori virulence factors and host interleukin (IL) polymorphisms are implicated in the pathogenesis of gastric adenocarcinoma (GCA), but have not been investigated together, in the South African context of low GCA incidence and high H pylori prevalence.