The Increased Risk of Renal Stones in Patients With COVID-19 Infection

Abstract

Background: The novel coronavirus disease (caused by SARS-CoV-2) has become a disaster all over the world. Based on available evidence, the main organ infected by this virus is the respiratory system; however, various other vital systems can also be affected by potential outcomes. One of the critical affected organs is the kidney. Objectives: This study aimed to report and reviewed Risk of Renal Stones in Patients With COVID-19 Infection. Methods: In the present study, we reviewed literature about the renal stone in patients with COVID-19 in six databases, including PubMed, Scopus, Web of Science, Springer, Ovid, and Google Scholar. Then, we reported six adult COVID-19 patients with no history of kidney disease and new-onset renal stones. Results: The rate of complicated ureteral stone disease significantly increased during the COVID-19 period. A few studies were available about renal stones, and mostly they were about the management of renal stones in patients infected with the coronavirus. However, in six patients, after being infected with COVID-19, the renal stone was recognized in patients. All the reported patients did not have a history of renal disease or other risk factors for renal stone formation. Conclusion: Kidney injury is a possible complication of coronavirus, but based on our search, renal stone without history was not reported. However, observed cases highlighted the possible effects of COVID-19 infection on kidney function changes. On the other hand, although supplementation with vitamins C and D may be beneficial for the management of COVID-19, is associated with risks. These molecules should be used with caution, particularly in prior stone formers. Physicians should be responsible for understanding the impact of potential treatments for COVID-19 on common pathologies within their scope of practice.