LONG TERM ADMINISTRATION OF EXOGENOUS OXYTOCIN: EFFECTS ON PREGNANCY RATE, AND EMBRYONIC AND FETAL LOSSES IN NILI-RAVI BUFFALOES

IF 0.6 4区生物学 Q3 AGRICULTURE, MULTIDISCIPLINARY

Journal of Animal and Plant Sciences Pub Date : 2020-01-01 DOI:10.36899/japs.2020.1.0005

S. Murtaza, A. Sattar, N. Ahmad, M. Ijaz, T. Omer, M. Akhtar, M. Shahzad

{"title":"LONG TERM ADMINISTRATION OF EXOGENOUS OXYTOCIN: EFFECTS ON PREGNANCY RATE, AND EMBRYONIC AND FETAL LOSSES IN NILI-RAVI BUFFALOES","authors":"S. Murtaza, A. Sattar, N. Ahmad, M. Ijaz, T. Omer, M. Akhtar, M. Shahzad","doi":"10.36899/japs.2020.1.0005","DOIUrl":null,"url":null,"abstract":"It is a common perception among dairy farmers in Pakistan that oxytocin (OT) injection negatively effects on buffalo reproduction parameters. Therefore, current study was conducted to investigate the outcomes of OT on numbers of AI per conception, pregnancy rate, embryonic and fetal losses (EFL). For this purpose, Nili-Ravi buffaloes (n=23) were randomly divided into three groups, G1; n=7 (control), G2; n=8 (low dose 10 i.u.) and G3; n=8 (high dose 30 i.u.). The OT injection was given twice daily at morning and evening milking until 154 days post calving. At heat, AI was performed. Ultrasonography and blood sampling were done on days 30, 45 and 60 post AI to monitor pregnancy and progesterone, respectively. Results showed significant (P≤0.05) increase of AI services per conception in G2 & G3 as compared to G1. Furthermore, results revealed that chances of the animals to become pregnant were 0.227 and 0.094 times in low (G2) and high doses (G3) in comparison to control (G1), respectively, and was lower significantly (P≤0.05). Similarly, pregnancy rate was remained unaffected and was non-significant (P>0.05) on day 45 vs day 30. However, it was significantly (P≤0.05) lower on day 60 vs day 30. Overall, pregnancy rate was decreased (P≤0.05) in oxytocin treatments comparable to control. Parity and days in milk had no significant effect on pregnancy rate among treatments (G1, G2 and G3), respectively. Moreover, EFL losses were non-significant (P>0.05) among treatments but losses trend was more in G2 & G3 parallel to G1. Result also showed non-significant (P>0.05) decrease in P4 on days 30 and 45 while significant (P≤0.05) on day 60 in G2 & G3 as compared to G1 among treatment groups. It may be concluded that long term OT injections of both low and high doses cause significant losses in terms of increase in AI services per conception and decrease pregnancy rate with higher EFL in Nili-Ravi buffaloes.","PeriodicalId":14924,"journal":{"name":"Journal of Animal and Plant Sciences","volume":"17 1","pages":"40-49"},"PeriodicalIF":0.6000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Animal and Plant Sciences","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.36899/japs.2020.1.0005","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"AGRICULTURE, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 2

Abstract

It is a common perception among dairy farmers in Pakistan that oxytocin (OT) injection negatively effects on buffalo reproduction parameters. Therefore, current study was conducted to investigate the outcomes of OT on numbers of AI per conception, pregnancy rate, embryonic and fetal losses (EFL). For this purpose, Nili-Ravi buffaloes (n=23) were randomly divided into three groups, G1; n=7 (control), G2; n=8 (low dose 10 i.u.) and G3; n=8 (high dose 30 i.u.). The OT injection was given twice daily at morning and evening milking until 154 days post calving. At heat, AI was performed. Ultrasonography and blood sampling were done on days 30, 45 and 60 post AI to monitor pregnancy and progesterone, respectively. Results showed significant (P≤0.05) increase of AI services per conception in G2 & G3 as compared to G1. Furthermore, results revealed that chances of the animals to become pregnant were 0.227 and 0.094 times in low (G2) and high doses (G3) in comparison to control (G1), respectively, and was lower significantly (P≤0.05). Similarly, pregnancy rate was remained unaffected and was non-significant (P>0.05) on day 45 vs day 30. However, it was significantly (P≤0.05) lower on day 60 vs day 30. Overall, pregnancy rate was decreased (P≤0.05) in oxytocin treatments comparable to control. Parity and days in milk had no significant effect on pregnancy rate among treatments (G1, G2 and G3), respectively. Moreover, EFL losses were non-significant (P>0.05) among treatments but losses trend was more in G2 & G3 parallel to G1. Result also showed non-significant (P>0.05) decrease in P4 on days 30 and 45 while significant (P≤0.05) on day 60 in G2 & G3 as compared to G1 among treatment groups. It may be concluded that long term OT injections of both low and high doses cause significant losses in terms of increase in AI services per conception and decrease pregnancy rate with higher EFL in Nili-Ravi buffaloes.

查看原文本刊更多论文

外源性催产素的长期管理:对受孕率的影响，胚胎和胎儿损失的水牛

巴基斯坦奶农普遍认为注射催产素(OT)会对水牛的繁殖参数产生负面影响。因此，本研究旨在探讨OT对每次受孕人工授精数、妊娠率、胚胎和胎儿损失(EFL)的影响。为此，将Nili-Ravi水牛(n=23)随机分为3组，G1组;n=7(对照)，G2;n=8(低剂量10 iu)和G3;N =8(高剂量30 iu)。每天早晚挤奶两次注射OT，直至产犊后154天。加热时进行人工智能。术后30、45、60 d分别行超声和采血监测妊娠和孕酮水平。结果显示，与G1相比，G2和G3的每胎人工智能服务显著(P≤0.05)增加。低剂量组(G2)和高剂量组(G3)的受孕率分别为对照组(G1)的0.227倍和0.094倍，显著低于对照组(P≤0.05)。第45天与第30天妊娠率无显著差异(P>0.05)。与第30天相比，第60天显著(P≤0.05)降低。总体而言，与对照组相比，催产素治疗组妊娠率降低(P≤0.05)。不同处理(G1、G2和G3)胎次和泌乳天数对妊娠率无显著影响。各组间EFL损失无显著性差异(P>0.05)，但与G1平行的G2和G3的损失趋势更多。结果显示，各组P4在第30、45天无显著性(P>0.05)降低，而G2、G3在第60天显著(P≤0.05)低于G1。由此可以得出结论，在尼利-拉维水牛中，长期注射低剂量和高剂量的外孕激素会导致每次受孕人工授精服务的增加和妊娠率的降低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Animal and Plant Sciences Multiple-

CiteScore

1.50

自引率

0.00%

发文量

128

审稿时长

6 months

期刊介绍： The Journal of Animal and Plant Sciences (JAPS) is a bi-monthly publication and is being published regularly since 1991 by the Pakistan Agricultural Scientists Forum (PAS FORUM). It publishes original research papers, review, extension/clinical articles on all aspects of animal (including fisheries/wildlife) and plant sciences, agricultural economics, rural sociology and other related subjects. The journal is read, abstracted and indexed by the abstracting/indexing agencies of international repute.