Investigating the Impact of Existing Pharmacovigilance Systems in Africa and How They Influence Adverse Drug Reaction Reporting by Nurses, Doctors and Pharmacists Working in Federal Government Hospitals - A Case Study of Nigeria

Larry L Mweetwa, K. Tshiamo, P. C. Adiukwu, Thatoyaone JKenaope, E. Oluwabusola
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Abstract

Background: The primary concern of Pharmacovigilance (PV) is to strengthen patient care and improve public safety in terms of effective use of medication. The aim of this research was to analyse the impact of the existing Pharmacovigilance systems in the African region and its significant impact on adverse drug reactions (ADRs) reported by the Doctors, Pharmacists, and Nurses working in Federal-State Hospitals in Nigeria. Methods: The research design opted for this study is constructed on a questionnaire-based quantitative design that has helped in determining the correlation between Healthcare Professionals (HCP) training and awareness of ADR reporting incidences in different federal government hospital settings of Nigeria. Results: The Pearson chi-square test of independence with df = 2 yields chi-square = 101.4 (n = 318, p < 0.05, phi = 0.565), affirming that there is a statistically significant relationship between the awareness of ADR-reporting system and professions. Conclusion: The findings revealed that a majority of pharmacist and doctors possessed a good knowledge regarding PV, whereas the majority of nurses had poor knowledge about PV.
调查非洲现有药物警戒系统的影响及其如何影响在联邦政府医院工作的护士、医生和药剂师报告药物不良反应——以尼日利亚为例
背景:药物警戒(PV)的主要关注点是加强患者护理和改善有效用药方面的公共安全。本研究的目的是分析非洲地区现有药物警戒系统的影响及其对尼日利亚联邦州立医院的医生、药剂师和护士报告的药物不良反应(adr)的重大影响。方法:本研究选择的研究设计基于基于问卷的定量设计,该设计有助于确定尼日利亚不同联邦政府医院环境中医疗保健专业人员(HCP)培训与不良反应报告发生率意识之间的相关性。结果:Pearson卡方独立性检验df = 2,卡方= 101.4 (n = 318, p < 0.05, phi = 0.565),证实不良反应报告制度意识与职业之间存在统计学意义上的关系。结论:调查结果显示,大部分药师和医生对PV有较好的了解,而大部分护士对PV的了解较差。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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