Tumor of proximal clavicle-solitary plasmacytoma of bone, an extremely rare case

Ju-Feng Hsueh, Karl Wu, Chih-Hung Chang
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Abstract

Solitary plasmacytoma of bone (SPB) was defined as solitary osteolytic bone lesion with plasma cells collection, and lack of evidence of systemic myeloma. SPB has a higher risk of multiple myeloma (MM) progression and lower survival rate compared to extramedullary plasmacytoma, which is another form of plasmacytoma with soft tissue infiltration. Most of the SPB were discovered at axial skeletons and diaphysis of long bones which red marrow is predominant. Thoracic and lumbar vertebrae are the most frequent disease distribution, while clavicle involvements were rarely seen. We reported a case of solitary plasmacytoma of proximal clavicle, an extremely rare presentation, sustained a pathologic fracture under a low-energy trauma mechanism treated with tumor excision, plate fixation, and adjuvant radiotherapy, and showed excellent stability and functional outcome in 1 year follow-up.
锁骨近端孤立性骨浆细胞瘤,极为罕见病例
孤立性骨浆细胞瘤(SPB)被定义为伴有浆细胞收集的孤立性溶骨病变,缺乏系统性骨髓瘤的证据。与髓外浆细胞瘤(另一种浸润软组织的浆细胞瘤)相比,SPB发生多发性骨髓瘤(MM)进展的风险较高,生存率较低。SPB多见于以红骨髓为主的中轴骨和长骨骨干。胸椎和腰椎是最常见的疾病分布,而累及锁骨很少见。我们报告了一例锁骨近端孤立性浆细胞瘤,这是一种极其罕见的病例,在低能创伤机制下发生病理性骨折,经肿瘤切除、钢板固定和辅助放疗治疗,并在1年的随访中显示出良好的稳定性和功能预后。
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