Prevalence, serotype distribution, and antimicrobial susceptibility profile of Streptococcus pneumoniae among patients with acute respiratory tract infection

Q2 Medicine

WHO South-East Asia journal of public health Pub Date : 2021-07-01 DOI:10.4103/WHO-SEAJPH.WHO-SEAJPH_58_21

D. Safari, N. Widhidewi, W. Paramaiswari, Anak Lila Paramasatiari, H.F. Maharani Putri, I. A. Asih Ratnadi, I. Agus Sastrawan

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引用次数: 1

Abstract

We investigated the nasopharyngeal (NP) carriage and antimicrobial susceptibility profile of Streptococcus pneumoniae among adults and children with acute respiratory tract infection (ARTI). NP swabs were collected from ARTI patients in Tabanan, Bali, Indonesia, in 2017. Serotyping of S. pneumoniae and antibiotic susceptibility profile were performed by multiplex sequential PCR and the disk diffusion method, respectively. Out of 200 ARTI patients, S. pneumoniae strains were carried by 22.6% and 2.4% of children (36/159) and adults (1/41), respectively. Serotype 6A/6B was the most common serotype among cultured strains (21%) followed by 19F (18%) and 14 (8%). Most isolates were susceptible to chloramphenicol (87%), followed by clindamycin (74%), erythromycin (72%), sulfamethoxazole-trimethoprim (59%), and tetracycline (44%). This finding provides baseline information on the serotype distribution of S. pneumoniae carriage among ARTI patients in Indonesia.

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急性呼吸道感染患者肺炎链球菌的患病率、血清型分布及抗菌药物敏感性分析

我们调查了急性呼吸道感染(ARTI)成人和儿童中肺炎链球菌的鼻咽部携带和抗菌药物敏感性。2017年从印度尼西亚巴厘岛塔巴南的ARTI患者中收集NP拭子。采用多重序列PCR和纸片扩散法分别进行肺炎链球菌血清分型和抗生素药敏分析。在200例ARTI患者中，儿童(36/159)和成人(1/41)携带肺炎链球菌的比例分别为22.6%和2.4%。血清型以6A/6B型最多(21%)，其次为19F型(18%)和14型(8%)。对氯霉素敏感的菌株最多(87%)，其次是克林霉素(74%)、红霉素(72%)、磺胺甲恶唑-甲氧苄啶(59%)和四环素(44%)。这一发现提供了印度尼西亚抗逆转录病毒治疗患者中肺炎链球菌血清型分布的基线信息。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

WHO South-East Asia journal of public health Medicine-Medicine (all)

CiteScore

4.10

自引率

0.00%

发文量

期刊介绍： The journal will cover technical and clinical studies related to health, ethical and social issues in field of Public Health, Epidemiology, primary health care, epidemiology, health administration, health systems, health economics, health promotion, public health nutrition, communicable and non-communicable diseases, maternal and child health, occupational and environmental health, social and preventive medicine. Articles with clinical interest and implications will be given preference.