A Systemic Review on Omicron Variant of SARS-CoV-2

Q3 Pharmacology, Toxicology and Pharmaceutics

Biomedical and Pharmacology Journal Pub Date : 2023-06-30 DOI:10.13005/bpj/2648

Manikantan Pappuswamy, Aditi Chaudhary, Anushka Shitut

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Abstract

As the new strains spread around the world, scientists have been trying to learn more about the different strains, especially Omicron, and how SARS-CoV2 acts in general. Studying historical trends of virus spread and the structure of the virus and its strains, as well as all the mechanisms it needs to survive, can help identify the symptoms and diagnose and treat the disease. The research has shown that the new strains, including Omicron, have a higher rate of mutation and transmissibility. Additionally, due to the rapid spread of the virus, there has not been a significant amount of time to understand the severity of the infection. To better understand the novel variants, a detailed analysis of the basic pathophysiology of the virus is needed. This includes transcriptome analysis for the recombination index to identify variation in the strand. This aided in the diagnostic process, and therapeutics for mutants of the virus could be treated. The Omicron strain is particularly threatening due to its rapid transmission rate and its property of immune evasion, which can make it less vulnerable to vaccination.

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SARS-CoV-2组粒变异的系统评价

随着新菌株在世界各地传播，科学家们一直在试图更多地了解不同的菌株，尤其是欧米克隆，以及SARS-CoV2的总体作用。研究病毒传播的历史趋势和病毒及其毒株的结构，以及它生存所需的所有机制，可以帮助识别症状，诊断和治疗疾病。研究表明，包括Omicron在内的新菌株具有更高的突变率和传播率。此外，由于病毒的迅速传播，没有足够的时间来了解感染的严重程度。为了更好地了解新的变异，需要对病毒的基本病理生理学进行详细分析。这包括转录组分析的重组指数，以确定在链的变化。这有助于诊断过程，并且可以治疗病毒的突变体。由于其快速传播速度和免疫逃避特性，欧米克隆菌株特别具有威胁性，这使得它对疫苗接种不那么脆弱。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biomedical and Pharmacology Journal Pharmacology, Toxicology and Pharmaceutics-Pharmacology

CiteScore

1.20

自引率

0.00%

发文量

189

期刊介绍： Biomedical and Pharmacology Journal (BPJ) is an International Peer Reviewed Research Journal in English language whose frequency is quarterly. The journal seeks to promote research, exchange of scientific information, consideration of regulatory mechanisms that affect drug development and utilization, and medical education. BPJ take much care in making your article published without much delay with your kind cooperation and support. Research papers, review articles, short communications, news are welcomed provided they demonstrate new findings of relevance to the field as a whole. All articles will be peer-reviewed and will find a place in Biomedical and Pharmacology Journal based on the merit and innovativeness of the research work. BPJ hopes that Researchers, Research scholars, Academician, Industrialists etc. would make use of this journal for the development of science and technology. Topics of interest include, but are not limited to: Biochemistry Genetics Microbiology and virology Molecular, cellular and cancer biology Neurosciences Pharmacology Drug Discovery Cardiovascular Pharmacology Neuropharmacology Molecular & Cellular Mechanisms Immunology & Inflammation Pharmacy.