Study of Oviduct Expression Specificct Glycoprotein1 (OVGP1) on Oocyte and Goat Follicles (Capra hircus)

Abstract

: Oviduct Specific Glycoprotein (OVGP1) is a glycoprotein that has been identified as a protein secreted from unciliated secretory epithelial cells in oviducts with a molecular weight of 65 kDa in goats. The expression of this protein is very dependent on estrogen levels and the oestrus phase of the species. On the other hand, glycoprotein plays an important role in the process of oocyte maturation, spermatozoa capitation, and early embryonic development. The purpose of this research was to find the location of OVGP1 expression in oocytes and follicles of kacang goat (Capra hircus), an endogenous goat from Indonesian . The methods used in this study are: immunocytochemical techniques to see OVGP1 expression on oocytes and on goat follicles. OVGP1 expression in goat oocytes (Capra hircus) observed using immunocytochemical techniques was detected in the cumulus ooporus section, the zona pellucida, perivitelline space, and plasma oocyte membrane, whereas in the follicle the OVGP1 expression observed using immunohistochemical methods showed that OVGP1 was expressed in granulosa cells, external and internal theca cells.