Antibiotic Sensitivity Of Acid Stressed Probiotic Lactobacillus Acidophilus Ncdc 291

Abstract

LAB (Lactic Acid Bacteria)-Lactobacillus acidophilus, a major inhabitant of gastrointestinal tract of human beings is used as a probiotic. Antibiotics taken during illness not only kill the disease causing microorganisms but also disrupt the normal microbial balance of the gut leading to a number of side effects and encouraging the patients to restore their natural gut microflora with the intake of probiotics. A well known probiotic Lactobacillus acidophilus NCDC 291 was used in the present study and its resistance towards antibiotics was determined at optimum pH and also by growing it under acid stressed conditions. Studies revealed that culture adapted to acid stressed conditions had increased resistance towards antibiotics than that grown at optimum pH.