Monomer elution model of composite resin material

Abstract

As a part of this study, a mathematical model based on two-compartment pharmacokinetic system with general fractional derivatives was developed. Its aim was to describe the release of BisGMA and TEGDMA monomers from composite core resin over three time periods. For this purpose, five Clearfil Photo Core resin samples were prepared and elution was measured using high performance liquid chromatography at 1, 7 and 28 days post-immersion in 75% ethanol. The findings confirmed good model fit to the data related to released monomer quantity.