Performance index – a new approach to the assessment of left ventricular systolic function

V. I. Pavliuk, О.A. Myshakivsky, M.V. Voytsekhivska, O. Zharinov
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Abstract

The aim – to develop a new approach to the assessment of LV systolic function – LV systolic performance index. To check correlation of this index with left ventricular ejection fraction determined by standard Simpson planimetric method.Materials and methods. A total of 121 patients were included into the study. We first determined left ventricular ejection fraction by Simpson method for each patient included in the study, and then determined VTI in the LVOT and myocardial motion velocity in four LV parts. We evaluated the correlation of these indices with left ventricular ejection fraction and derived a hybrid index of LV systolic function performance based on stepwise multiple regression.Results and discussion. The myocardial velocity in four LV parts, its averaged value and velocity time integral in LVOT not only showed a high level of correlation with left ventricular ejection fraction, but appeared also its independent predictors in multivariate analysis. The hybrid formula «0.7 × Sum of MV + VTI» derived in our study provides an index of LV systolic function performance. A good correlation of the new index with left ventricular ejection fraction determined by Simpson (Kendall’s tau 0.818; p <0.00001) was revealed.Conclusions. We proposed a new index of LV systolic function estimation and showed that it allows reliable estimation of LV systolic function in various myocardial pathologies with less time.
性能指标——评价左心室收缩功能的新方法
目的:建立一种评价左室收缩功能的新方法——左室收缩功能指数。目的:探讨该指标与标准辛普森平面法测定的左室射血分数的相关性。材料和方法。共有121名患者被纳入研究。我们首先用Simpson法测定入组患者的左室射血分数,然后测定LVOT中的VTI和四个左室部位的心肌运动速度。我们评估了这些指标与左心室射血分数的相关性,并基于逐步多元回归推导了左室收缩功能表现的混合指数。结果和讨论。左室4个部位的心肌速度及其平均值、LVOT的速度时间积分不仅与左室射血分数有较高的相关性,而且在多变量分析中也成为其独立的预测因子。本研究导出的混合公式“0.7 × MV + VTI之和”提供了左室收缩功能表现的指标。新指标与Simpson测定的左室射血分数有较好的相关性(Kendall’s tau 0.818;p <0.00001)。我们提出了一种新的左室收缩功能估计指标,并表明它可以在更短的时间内可靠地估计各种心肌病理的左室收缩功能。
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