Simultaneous Determination of Phenolic and Steroidal Estrogens in Water of Songhua River, Northeastern China

Abstract

This paper describes a simple and sensitive method for determining estrogen (E1), β-estradiol (E2), estriol (E3), 17α-ethynylestradiol (EE2), diethylstilbestrol (DES), 4-tert-octyphenol (OP), 4-n-nonylphenol (NP), nonylphenol mono- to di-ethoxylates (NP1EO, NP2EO), bisphenol A (BPA) in water samples of Songhua River in China. The survey was preceded by selecting extraction methods, clean-up procedures for the simultaneous GC-MS determination of all examined EDCs in water samples. The limits of detection (LOD) of all the target compounds were 0.052~1.5ng/L. The concentration levels of five steroidal estrogens, E1, E2, E3, EE2, DES in water samples of Songhua River were ND.~15.78 ng/L, ND.~6.63ng/L, ND., ND.~34.70ng/L and ND.~6.75ng/L, respectively and the concentration levels of five phenolic endocrine disrupting chemicals, OP, 4-n-NP, NP1EO, BPA and NP2EO, in water samples were 1.84~15.28 ng/L, 0.18~6.82 ng/L, 6.06~126.09 ng/L, 8.84~329.47 ng/L and 4.68~123.30 ng/L, respectively.