Neoplasms of the appendix: An experience of a tertiary hospital in Southwestern Nigeria

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
M. Ajani, S. Omenai, O. Iyapo
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引用次数: 1

Abstract

Background: The appendix is a vestigial tube-like organ. Its exact physiological function is unknown. Appendectomies are done usually following a clinical diagnosis of acute appendicitis. Neoplasms can arise from this organ as well. Carcinoids are the most common neoplasms arising commonly at the tips. This retrospective review of neoplasms of the appendix was aimed at identifying the incidence and describing the histological variants of neoplasms of the appendix in our environment. Materials and Methods: This study was a 10-year retrospective review of all appendectomy specimens submitted to the Department of Pathology, University College Hospital, Ibadan, Nigeria, from January 1, 2009, to December 31, 2018. Microscopy was done examining the longitudinal sections from the tip to the base of the appendix. The histological diagnosis was extracted from the records in the department and classified using the WHO classification of tumors of the appendix (2019). Patients' biodata such as age and sex were also extracted. The data were analyzed for frequency distribution using SPSS 23. Results: The incidence of neoplasms in the appendix was 0.84% of the 1071 appendectomies received in our department over the study period. Low-grade appendiceal mucinous neoplasm (LAMN) was the most common histological variant accounting for 55.5% of neoplasms, followed by metastatic carcinoma at 22.2% and carcinoids at 11.1%. There was a female preponderance of 77.8%. Conclusion: Neoplasms of the appendix are rare in our environment, and LAMN was the most common neoplasm of the appendix in our institution. There is a female preponderance among patients with appendiceal neoplasms.
阑尾肿瘤:尼日利亚西南部一家三级医院的经验
背景:阑尾是一个退化的管状器官。其确切的生理功能尚不清楚。阑尾切除术通常在临床诊断为急性阑尾炎后进行。肿瘤也可以从这个器官产生。类癌是最常见的肿瘤,常见于鼻尖。本回顾性回顾阑尾肿瘤的目的是确定发病率和描述阑尾肿瘤的组织学变异在我们的环境。材料和方法:本研究对2009年1月1日至2018年12月31日期间提交给尼日利亚伊巴丹大学学院医院病理科的所有阑尾切除术标本进行了为期10年的回顾性分析。显微镜检查从阑尾尖端到底部的纵剖面。从科室病历中提取组织学诊断,采用WHO《阑尾肿瘤分类(2019)》进行分类。同时提取患者的年龄、性别等生物数据。使用SPSS 23对数据进行频率分布分析。结果:在我科1071例阑尾切除术中,阑尾肿瘤的发生率为0.84%。低级别阑尾粘液瘤(LAMN)是最常见的组织学变异,占肿瘤的55.5%,其次是转移癌(22.2%)和类癌(11.1%)。其中女性占77.8%。结论:阑尾肿瘤在本院少见,LAMN是本院最常见的阑尾肿瘤。阑尾肿瘤患者以女性居多。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Clinical Sciences
Journal of Clinical Sciences MEDICINE, GENERAL & INTERNAL-
自引率
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15
审稿时长
45 weeks
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