Uncertainty-based Gompertz growth model for tumor population and its numerical analysis

IF 2.2 Q1 MATHEMATICS, APPLIED
Aadil Rashid Sheergojri, P. Iqbal, P. Agarwal, Necati Ozdemir
{"title":"Uncertainty-based Gompertz growth model for tumor population and its numerical analysis","authors":"Aadil Rashid Sheergojri, P. Iqbal, P. Agarwal, Necati Ozdemir","doi":"10.11121/ijocta.2022.1208","DOIUrl":null,"url":null,"abstract":"For treating cancer, tumor growth models have shown to be a valuable resource, whether they are used to develop therapeutic methods paired with process control or to simulate and evaluate treatment processes. In addition, a fuzzy mathematical model is a tool for monitoring the influences of various elements and creating behavioral assessments. It has been designed to decrease the ambiguity of model parameters to obtain a reliable mathematical tumor development model by employing fuzzy logic.The tumor Gompertz equation is shown in an imprecise environment in this study. It considers the whole cancer cell population to be vague at any given time, with the possibility distribution function determined by the initial tumor cell population, tumor net population rate, and carrying capacity of the tumor. Moreover, this work provides information on the expected tumor cell population in the maximum period. This study examines fuzzy tumor growth modeling insights based on fuzziness to reduce tumor uncertainty and achieve a degree of realism. Finally, numerical simulations are utilized to show the significant conclusions of the proposed study.","PeriodicalId":37369,"journal":{"name":"International Journal of Optimization and Control: Theories and Applications","volume":"32 1","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2022-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"11","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Optimization and Control: Theories and Applications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11121/ijocta.2022.1208","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATHEMATICS, APPLIED","Score":null,"Total":0}
引用次数: 11

Abstract

For treating cancer, tumor growth models have shown to be a valuable resource, whether they are used to develop therapeutic methods paired with process control or to simulate and evaluate treatment processes. In addition, a fuzzy mathematical model is a tool for monitoring the influences of various elements and creating behavioral assessments. It has been designed to decrease the ambiguity of model parameters to obtain a reliable mathematical tumor development model by employing fuzzy logic.The tumor Gompertz equation is shown in an imprecise environment in this study. It considers the whole cancer cell population to be vague at any given time, with the possibility distribution function determined by the initial tumor cell population, tumor net population rate, and carrying capacity of the tumor. Moreover, this work provides information on the expected tumor cell population in the maximum period. This study examines fuzzy tumor growth modeling insights based on fuzziness to reduce tumor uncertainty and achieve a degree of realism. Finally, numerical simulations are utilized to show the significant conclusions of the proposed study.
基于不确定性的肿瘤种群Gompertz生长模型及其数值分析
对于治疗癌症而言,肿瘤生长模型已被证明是一种宝贵的资源,无论是用于开发与过程控制相结合的治疗方法,还是用于模拟和评估治疗过程。此外,模糊数学模型是监测各种因素影响和创建行为评估的工具。利用模糊逻辑,减少模型参数的模糊性,得到可靠的肿瘤发展数学模型。在本研究中,肿瘤Gompertz方程是在一个不精确的环境中显示的。它认为整个肿瘤细胞群在任何给定时间都是模糊的,其可能性分布函数由初始肿瘤细胞群、肿瘤净种群率和肿瘤的承载能力决定。此外,这项工作还提供了最大周期内预期肿瘤细胞群的信息。本研究探讨基于模糊性的模糊肿瘤生长建模见解,以减少肿瘤的不确定性,并达到一定程度的真实感。最后,通过数值模拟验证了本文研究的重要结论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
3.30
自引率
6.20%
发文量
13
审稿时长
16 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信