Advancements in repetitive transcranial magnetic Stimulation for ischemic stroke rehabilitation

Abstract

Despite significant improvements in acute stroke management, numerous stroke patients continue to experience wide-ranging disabilities, posing a severe global healthcare problem. Effective neuro-rehabilitation is critical for reduction of disability and improvement of life quality after stroke. Rapid developments in several post-ischemic stroke rehabilitation techniques, including magnetic, ultrasonic, optogenetic and electronic modalities, have been achieved in recent years. Repetitive transcranial magnetic stimulation has shown promising therapeutic efficacy in ischemic stroke rehabilitation during the last two decades. This review provides a detailed summary of the development, safety and efficacy of transcranial magnetic stimulation devices, current experimental models and mechanisms of repetitive transcranial magnetic stimulation in the context of ischemic stroke rehabilitation.