Thoracic CT Scan Findings in Patients with Confirmed Hematologic Malignancies Admitted to the Hospital with Acute Pulmonary Symptoms

IF 0.4 Q4 ONCOLOGY

International Journal of Cancer Management Pub Date : 2023-05-03 DOI:10.5812/ijcm-132914

Shadi nouri, Navid Mirhosseini, Nazanin Naghibi, M. Hasanian

{"title":"Thoracic CT Scan Findings in Patients with Confirmed Hematologic Malignancies Admitted to the Hospital with Acute Pulmonary Symptoms","authors":"Shadi nouri, Navid Mirhosseini, Nazanin Naghibi, M. Hasanian","doi":"10.5812/ijcm-132914","DOIUrl":null,"url":null,"abstract":"Background: Hematologic malignancies are the fifth most common malignancies worldwide. Pulmonary symptoms are among the patient’s common complaints. Early diagnosis based on patient symptoms, laboratory testing, and imaging may lead to an appropriate therapeutic approach. Objectives: To evaluate thoracic computed tomography (CT) scan findings in known cases of hematologic malignancy with acute respiratory symptoms. Methods: A cross-sectional study was conducted on 200 patients with hematologic malignancies admitted to Khansari cancer center for acute pulmonary symptoms, from December 2019 to May 2020. Collected data included demographic data, physical examination, laboratory tests and findings of thoracic CT images. Descriptive analysis and chi-Square test were performed to analyze the data using SPSS version 20. Results: Non-Hodgkin lymphoma was the most common malignancy, accounting for 48% of total cases. The most common radiological findings included atelectasis (49%), followed by pleural effusion (42%), mediastinal lymphadenopathy (38.5%), consolidation (37%), and ground-glass opacities (33.5%). Mediastinal lymphadenopathy was more prevalent in patients diagnosed with lymphoma. Among pulmonary pathologies, pneumonia was the most prevalent disease (41.5%), followed by small airway disease (13.5%), mediastinal lymphadenopathy (12.5%), chronic pulmonary disease (6.5%), and pulmonary metastasis (6%). Normal thoracic CT scan was detected in 20% of participants. Overall assessment of clinical symptoms, laboratory tests, and imaging findings did not lead to the diagnosis of acute lung involvement in 5.5% of study participants, because complete clinical data were not available in some participants. Conclusions: Assessment of the most common thoracic imaging findings in patients diagnosed with hematologic malignancies, may help make better diagnosis and planning of a rapid therapeutic approach.","PeriodicalId":44764,"journal":{"name":"International Journal of Cancer Management","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Cancer Management","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5812/ijcm-132914","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Hematologic malignancies are the fifth most common malignancies worldwide. Pulmonary symptoms are among the patient’s common complaints. Early diagnosis based on patient symptoms, laboratory testing, and imaging may lead to an appropriate therapeutic approach. Objectives: To evaluate thoracic computed tomography (CT) scan findings in known cases of hematologic malignancy with acute respiratory symptoms. Methods: A cross-sectional study was conducted on 200 patients with hematologic malignancies admitted to Khansari cancer center for acute pulmonary symptoms, from December 2019 to May 2020. Collected data included demographic data, physical examination, laboratory tests and findings of thoracic CT images. Descriptive analysis and chi-Square test were performed to analyze the data using SPSS version 20. Results: Non-Hodgkin lymphoma was the most common malignancy, accounting for 48% of total cases. The most common radiological findings included atelectasis (49%), followed by pleural effusion (42%), mediastinal lymphadenopathy (38.5%), consolidation (37%), and ground-glass opacities (33.5%). Mediastinal lymphadenopathy was more prevalent in patients diagnosed with lymphoma. Among pulmonary pathologies, pneumonia was the most prevalent disease (41.5%), followed by small airway disease (13.5%), mediastinal lymphadenopathy (12.5%), chronic pulmonary disease (6.5%), and pulmonary metastasis (6%). Normal thoracic CT scan was detected in 20% of participants. Overall assessment of clinical symptoms, laboratory tests, and imaging findings did not lead to the diagnosis of acute lung involvement in 5.5% of study participants, because complete clinical data were not available in some participants. Conclusions: Assessment of the most common thoracic imaging findings in patients diagnosed with hematologic malignancies, may help make better diagnosis and planning of a rapid therapeutic approach.

查看原文本刊更多论文

以急性肺部症状入院的确诊血液恶性肿瘤患者的胸部CT表现

背景:血液恶性肿瘤是世界上第五大最常见的恶性肿瘤。肺部症状是病人的常见主诉之一。基于患者症状、实验室检查和影像学的早期诊断可能导致适当的治疗方法。目的:评价已知血液恶性肿瘤合并急性呼吸道症状的胸部CT表现。方法:对2019年12月至2020年5月期间因急性肺部症状入住Khansari癌症中心的200例血液系统恶性肿瘤患者进行横断面研究。收集的资料包括人口统计资料、体格检查、实验室检查和胸部CT图像的发现。采用SPSS version 20对数据进行描述性分析和卡方检验。结果:非霍奇金淋巴瘤是最常见的恶性肿瘤，占总病例的48%。最常见的影像学表现包括肺不张(49%)，其次是胸腔积液(42%)、纵隔淋巴结病(38.5%)、实变(37%)和毛玻璃混浊(33.5%)。纵膈淋巴结病在诊断为淋巴瘤的患者中更为普遍。在肺部疾病中，肺炎是最常见的疾病(41.5%)，其次是小气道疾病(13.5%)、纵隔淋巴结病(12.5%)、慢性肺病(6.5%)和肺转移(6%)。20%的参与者胸部CT扫描正常。5.5%的研究参与者对临床症状、实验室检查和影像学结果进行了全面评估，但没有诊断出急性肺部受累，因为一些参与者没有完整的临床资料。结论:评估血液学恶性肿瘤患者最常见的胸部影像学表现，可能有助于更好地诊断和制定快速治疗方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

International Journal of Cancer Management ONCOLOGY-

CiteScore

1.10

自引率

0.00%

发文量

期刊介绍： International Journal of Cancer Management (IJCM) publishes peer-reviewed original studies and reviews on cancer etiology, epidemiology and risk factors, novel approach to cancer management including prevention, diagnosis, surgery, radiotherapy, medical oncology, and issues regarding cancer survivorship and palliative care. The scope spans the spectrum of cancer research from the laboratory to the clinic, with special emphasis on translational cancer research that bridge the laboratory and clinic. We also consider original case reports that expand clinical cancer knowledge and convey important best practice messages.