MICROBIOME OF THE UPPER RESPIRATORY TRACT IN INFANTS AND PRESCHOOL CHILDREN

Q4 Medicine

Pediatriya - Zhurnal im G.N. Speranskogo Pub Date : 2023-02-17 DOI:10.24110/0031-403x-2023-102-1-98-105

T.I. Kurdiukova, O.N. Krasnorutskaia

{"title":"MICROBIOME OF THE UPPER RESPIRATORY TRACT IN INFANTS AND PRESCHOOL CHILDREN","authors":"T.I. Kurdiukova, O.N. Krasnorutskaia","doi":"10.24110/0031-403x-2023-102-1-98-105","DOIUrl":null,"url":null,"abstract":"This bibliographical review provides an analysis of modern domestic and foreign sources on the microbiome of the upper respiratory tract (URT) in children of early and preschool ages. It was discovered using the genetic sequencing method that the mucous membranes of the URT are inhabited by a wide range of bacteria belonging to the genera Firmicutes, Actinobacteria, Bacteroidetes, Proteobacteria and Fusobacteria, with the predominant genera Moraxella, Haemophilus, Streptococcus, Flavobacteria, Corynebacterium and Neisseria. Colonization of the URT begins at birth and continues into the first 3 years of a child's life. It is influenced by the method of delivery as well as the environmental microbiome in the baby's environment. Normal microbiota has colonization resistance, prevents the colonization of pathogenic flora, and also competes with pathogens. It has been proven that microbiota profiles in infants and preschool children vary depending on the season. One of the important areas of research is the assessment of the impact of antiseptics and antibiotics, as well as probiotic preparations, on the microbiota.","PeriodicalId":39654,"journal":{"name":"Pediatriya - Zhurnal im G.N. Speranskogo","volume":"6 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatriya - Zhurnal im G.N. Speranskogo","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24110/0031-403x-2023-102-1-98-105","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

This bibliographical review provides an analysis of modern domestic and foreign sources on the microbiome of the upper respiratory tract (URT) in children of early and preschool ages. It was discovered using the genetic sequencing method that the mucous membranes of the URT are inhabited by a wide range of bacteria belonging to the genera Firmicutes, Actinobacteria, Bacteroidetes, Proteobacteria and Fusobacteria, with the predominant genera Moraxella, Haemophilus, Streptococcus, Flavobacteria, Corynebacterium and Neisseria. Colonization of the URT begins at birth and continues into the first 3 years of a child's life. It is influenced by the method of delivery as well as the environmental microbiome in the baby's environment. Normal microbiota has colonization resistance, prevents the colonization of pathogenic flora, and also competes with pathogens. It has been proven that microbiota profiles in infants and preschool children vary depending on the season. One of the important areas of research is the assessment of the impact of antiseptics and antibiotics, as well as probiotic preparations, on the microbiota.

查看原文本刊更多论文

婴幼儿和学龄前儿童上呼吸道微生物群

这篇文献综述提供了对早期和学龄前儿童上呼吸道(URT)微生物组的现代国内外来源的分析。通过基因测序方法发现，上颌上颌窦粘膜上栖息着广泛的细菌，分别属于厚壁菌门、放线菌门、拟杆菌门、变形菌门和梭杆菌门，其中莫拉菌属、嗜血杆菌属、链球菌属、黄杆菌属、杆状杆菌属和奈瑟菌属。上呼吸道的殖民化始于出生，并持续到孩子生命的前3年。它受分娩方式以及婴儿环境中的环境微生物组的影响。正常的微生物群具有定植抗性，可以阻止病原菌群的定植，并与病原体竞争。已经证明，婴儿和学龄前儿童的微生物群概况因季节而异。其中一个重要的研究领域是评估防腐剂和抗生素以及益生菌制剂对微生物群的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Pediatriya - Zhurnal im G.N. Speranskogo Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.60

自引率

0.00%

发文量

150

期刊介绍： Journal “Pediatria” named after G.N. Speransky (the official short names of the Journal are “Journal «Pediatria»,” “Pediatria,” and “«Pediatria,» the Journal”) is the oldest Soviet-and-Russian (in the Russian Federation, the CIS and former Soviet Union) scientific and practical medical periodical assigned for pediatricians that is published continuously since May, 1922, and distributed worldwide. Our mission statement specifies that we aim to the ‘raising the level of skills and education of pediatricians, organizers of children’s health protection services, medicine scientists, lecturers and students of medical institutes for higher education, universities and colleges worldwide with an emphasis on Russian-speaking audience and specific, topical problems of children’s healthcare in Russia, the CIS, Baltic States and former Soviet Union Countries and their determination with the use of the World’s best practices in pediatrics.’ As part of this objective, the Editorial of the Journal «Pediatria» named after G.N. Speransky itself adopts a neutral position on issues treated within the Journal. The Journal serves to further academic discussions of topics, irrespective of their nature - whether religious, racial-, gender-based, environmental, ethical, political or other potentially or topically contentious subjects. The Journal is registered with the ISSN, - the international identifier for serials and other continuing resources, in the electronic and print world: ISSN 0031-403X (Print), and ISSN 1990-2182 (Online). The Journal was founded by the Academician, Dr. Georgiy Nestorovich SPERANSKY, in May, 1922. Now (since 1973) the Journal bears his honorary name.