{"title":"Use of Recurrence Plots to Find Mutations in Deoxyribonucleic Acid Sequences","authors":"D. E. Rivas-Cisneros","doi":"10.25088/complexsystems.32.1.89","DOIUrl":null,"url":null,"abstract":"This paper examines the use of recurrence plots to find changes in the deoxyribonucleic acid (DNA) sequence. The DNA sequence is entered into the recurrence plot algorithm in codons and not consecutively, in order to make it easier to find the nucleotide change. The results show that the codon arrangement makes it easy to identify two types of mutations, insertion and deletion, by means of the recurrence plot. It is also shown that the recurrence plot of a short codon sequence has a homogeneous structure. Similarly, a comparison is made with the digital signal processing methodology. Some limitations are the number of codons that can be entered into the algorithm because computationally it becomes very slow and matrix issues, which are mentioned in the discussion section.","PeriodicalId":50871,"journal":{"name":"Advances in Complex Systems","volume":null,"pages":null},"PeriodicalIF":0.7000,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Complex Systems","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.25088/complexsystems.32.1.89","RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MATHEMATICS, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
引用次数: 0
Abstract
This paper examines the use of recurrence plots to find changes in the deoxyribonucleic acid (DNA) sequence. The DNA sequence is entered into the recurrence plot algorithm in codons and not consecutively, in order to make it easier to find the nucleotide change. The results show that the codon arrangement makes it easy to identify two types of mutations, insertion and deletion, by means of the recurrence plot. It is also shown that the recurrence plot of a short codon sequence has a homogeneous structure. Similarly, a comparison is made with the digital signal processing methodology. Some limitations are the number of codons that can be entered into the algorithm because computationally it becomes very slow and matrix issues, which are mentioned in the discussion section.
期刊介绍:
Advances in Complex Systems aims to provide a unique medium of communication for multidisciplinary approaches, either empirical or theoretical, to the study of complex systems. The latter are seen as systems comprised of multiple interacting components, or agents. Nonlinear feedback processes, stochastic influences, specific conditions for the supply of energy, matter, or information may lead to the emergence of new system qualities on the macroscopic scale that cannot be reduced to the dynamics of the agents. Quantitative approaches to the dynamics of complex systems have to consider a broad range of concepts, from analytical tools, statistical methods and computer simulations to distributed problem solving, learning and adaptation. This is an interdisciplinary enterprise.